To induce tolerance.
References in periodicals archive ?
Under SQZ's tolerance programme, including its new T1D programme, auto-antigens are delivered to cells in a way that leverages naturally occurring biological processes to tolerize the patient's immune system and potentially eliminate its ability to attack healthy tissue.
Based on a mouse model it has been shown that HLAG-positive tumor cells develop and tolerize the host antitumor immune response in vivo [108].
Toll-like receptor-7 tolerizes malignant B cells and enhances killing by cytotoxic agents.