Tolazoline (1.0 X [10.sup.-9] M) and Propanolol (1.0 X [10.sup.-9] M) were used in cases of relaxation.
China) Hexamethonium (BDH), Nifedipine (Alison's Drug Company), Tolazoline (Sigma) Propanol (Sigma).
Its effect was blocked by tolazoline (1.0 X [10.sup.-9] M) and propranolol (1.0 X [10.sup.-9] M).
The effect was blocked by tolazoline (5.1 X [10.sup.-7] M) while propranolol (3.4 X [10.sup.-8] M) reduced it by 50.0%.
Other less specific reversal agents, such as yohimbine and tolazoline, can be used to antagonize xylazine, the least potent of the alpha-2 agonists.
If carfentanil is combined with xylazine, the effects of xylazine should be antagonized by either atipamezole (Antisedan[R] 5 mg/ml, Orion Pharma Animal Health, Turku, Finland) at 1 mg per 10 mg xylazine, yohimbine (Antagonil[R] 5 mg/ml, Wildlife Pharmaceuticals Inc.) at 1 mg per mg xylazine, or tolazoline (Tolazoline[R] 100 mg/ml, Lloyd Laboratories, Shenandoa, Iowa, USA) at 15 mg per mg xylazine (Roffe et al.