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tizanidine/ti·zan·i·dine/ (ti-zan´ĭ-dēn″) an antispastic used as the hydrochloride salt in the treatment of spasticity related to multiple sclerosis or spinal cord injury.
a skeletal muscle relaxant and a2-adrenergic agonist.
indications It is used in the acute/intermittent management of increased muscle tone associated with spasticity.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Adverse effects include dry mouth, vomiting, increased ALT, abnormal liver function studies, constipation, somnolence, dizziness, speech disorder, dyskinesia, nervousness, hallucination, psychosis, urinary tract infection, blurred vision, urinary frequency, flulike syndrome, pharyngitis, and rhinitis.