Like that of urodeles, the process can be categorized into the following steps: (1) wound closure and healing, (2) formation of wound epidermis, (3) formation of proliferative blastema cells, and (4) cellular differentiation and morphogenesis that leads to tissue restoration (Akimenko et al, 2003; Fig.
In spite of these differences between the adult fin and larval finfold, we previously suggested that their tissue restoration processes are similar in that they both form a specialized epithelial cover with a distinct molecular identity and that apparent activation of cell proliferation occurs in both in response to wounding (Kawakami et ai, 2004).
A number of techniques have been developed for processing porous scaffolds for bone
tissue restoration, but most of them are involved typically incorporation of volatile organic particles in the inorganic HAp powders, gel casting of foams, three-dimensional printing, and replication of polymer sponge or foams [12-14].
Stocum, Strategies for
tissue restoration, comments in wound repair and regeneration, Regeneration biology and Engineering, Vol.
(19.) Stocun D L, "Regenerative Biology and Engineering : Stategies for
Tissue Restoration", Comment in Wound Repair and Regeneration, 1998, Jul-Aug, 6(4) : 273-5.