Like that of urodeles, the process can be categorized into the following steps: (1) wound closure and healing, (2) formation of wound epidermis, (3) formation of proliferative blastema cells, and (4) cellular differentiation and morphogenesis that leads to tissue restoration (Akimenko et al, 2003; Fig.
In spite of these differences between the adult fin and larval finfold, we previously suggested that their tissue restoration processes are similar in that they both form a specialized epithelial cover with a distinct molecular identity and that apparent activation of cell proliferation occurs in both in response to wounding (Kawakami et ai, 2004).
A number of techniques have been developed for processing porous scaffolds for bone tissue restoration
, but most of them are involved typically incorporation of volatile organic particles in the inorganic HAp powders, gel casting of foams, three-dimensional printing, and replication of polymer sponge or foams [12-14].
Stocum, Strategies for tissue restoration
, comments in wound repair and regeneration, Regeneration biology and Engineering, Vol.
(19.) Stocun D L, "Regenerative Biology and Engineering : Stategies for Tissue Restoration
", Comment in Wound Repair and Regeneration, 1998, Jul-Aug, 6(4) : 273-5.