tissue macrophage

tissue macrophage

Etymology: OFr, tissu + Gk, makros, large, phagein, to eat
a large, mobile, highly phagocytic cell derived from monocytes. These cells become mobile when stimulated by inflammation and migrate to the affected area. They are resident in specific tissues (for example, alveolar macrophages in the lungs).
References in periodicals archive ?
Histiocytic disorders are a group of diseases that occur when there is an overproduction of tissue macrophage cells known as histiocytes.
ADMSC: adipose mesenchymal stem cell; PC1: Prohormone Convertase 1; ILC-2: group 2 innate lymphoid cells; BMP7: bone morphogenic protein 7; EID1: EP300-interacting inhibitor of differentiation 1; M2 ATM: adipose tissue macrophage 2; FGF21: fibroblastic growth factor 21; PPARg: peroxisome proliferator-activated receptor gamma; TR: thyroid receptors; FXR: farnesoid X receptor; BNP: brain natriuretic factor.
Saltiel, "Obesity induces a phenotypic switch in adipose tissue macrophage polarization," The Journal of Clinical Investigation, vol.
Oral exposure to cadmium chloride triggers an acute inflammatory response in the intestines of mice, initiated bythe over-expression of tissue macrophage inflammatory protein-2 mRNA.
Abnormal differentiation of tissue macrophage populations in osteopetrosis (op) mice defective m the production of macrophage colony-stimulanting factor.
We want to understand the age-associated changes in gene expression and epigenetic identity of tissue macrophage populations with the ultimate goal to reverse age dependent decline in self-renewal and function.
CSF1R, a cell-surface receptor for its ligands, colony-stimulating factor 1 and IL-34, is thought to play an important role as regulator of the development, morphology, survival, and functions of tissue macrophages as well as tumor-associated macrophages.
This is the first report demonstrating that tissue macrophages can be infected and that they respond to antiretroviral therapy,' Honeycutt said.
The first wave of macrophages is generated during early embryogenesis and is derived from Yolk Sac progenitors, giving rise to physiological tissue macrophages (named microglia, Langerhans cells, Kupffer cells and alveolar macrophages) with the marked ability to self-renew in the periphery.
Tissue macrophages (TiMas) continuously phagocytize and digest apoptotic cells and tissue debris.
Apoptotic or aged neutrophils are cleared primarily by resident tissue macrophages in the liver, spleen, and bone marrow [10,11].
Whether tissue macrophages are self-renewing or continuously replenished from the bone marrow still is a matter of debate.