KLK1

(redirected from tissue kallikrein)
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Related to tissue kallikrein: kallikrein serine protease 1

KLK1

A gene on chromosome 19q13.3 that encodes a serine protease with diverse physiological functions, which may also have a role in carcinogenesis. KLK1 releases the vasoactive peptide Lys-bradykinin from low molecular weight kininogen.
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1]-proteinase inhibitor and tissue kallikrein in controlling allergic ovine airway hyperresponsiveness.
Aberrant human tissue kallikrein levels in the stratum corneum and se rum of patients with psoriasis: dependence on phenotype, severity and therapy.
The new human tissue kallikrein gene family: structure, function, and association to disease.
5] Nonstandard abbreviations: FIGO, Federation Internationale des Gynaecologistes et Obstetristes; hK, human tissue kallikrein protein; PFS, progression-free survival; OS, overall survival; HR, hazard ratio.
Human tissue kallikreins (hKs) (6) comprise a subgroup of 15 homologous secreted serine proteases encoded by a tightly clustered multigene family on the long arm of chromosome 19 (KLK1-KLK15)'.
The human tissue kallikrein family includes 15 genes (KLK1 to KLK15) [6] clustered in tandem on chromosome 19813.
Expression and localization of tissue kallikrein mRNAs in human epidermis and appendages.
She cloned and characterized a novel serine protease gene, human tissue kallikrein 10 (hK10), and developed an immunoassay to measure hK10 protein concentrations in biological fluids and tissue extracts.