: cyanoacrylate glue and fibrin sealant.
In peripheral corneal perforations and descemetoceles and when the perforation is relatively small (i.e., it does not require full-sized penetrating keratoplasty but is too large for tissue adhesive
) [1, 15, 16], tectonic corneoscleral patch grafting is performed as a temporary or definitive treatment.
Hence, it is reasonable to try to replace the use of sutures with a tissue adhesive
that can be applied to the eye surface.
Comparison of the bacteriostatic effects, corneal cytotoxicity, and the ability to seal corneal incisions among three different tissue adhesives
The results of this study reinforce the hypothesis that cyanoacrylate tissue adhesives
are an effective barrier to Gram-positive bacterial penetration in the in vitro mode (137-41).
(cyanoacrylates) are extensively used in medicine, but it was only after 2002 that studies showed their superiority to suture closure in circumcisions.
Thus, various unconventional methods are used in patients with bleeding disorders, particularly the application of fibrin sealants and tissue adhesives
, as adjunctive treatment or in some cases primary treatment.
The new business, which is subject to European Union regulatory approval, will address the market for surgical sealants, adhesion barriers and tissue adhesives
. According to the partners this is a large and underserved market of more than 100m annual surgical procedures worldwide.
It also encompasses Baymedix FG wound-dressing foams manufactured by Bayer MaterialScience AG, and Baymedix AT topical tissue adhesives
currently in development.
Together with the two products launched into the US in December 2009, this approval now provides AMS with a broad range of topical tissue adhesives
for closure of trauma wounds and surgical incisions for the US Acute Care and Alternate Site market segments, it said.
It also encompasses Baymedix FG foams for wound dressings and Baymedix AT topical tissue adhesives
that are currently in development.
This second edition has expanded the scope and depth of the original text and includes all types of tissue adhesives
, their proper indications and their uses.