They found that penicillin and tilmicosin
may offer the most effective treatments.
The minimum inhibitory concentration of tilmicosin
and tylosin for Mycoplasma gallisepticum and Mycoplasma synoviae and a comparison of their efficacy in the control of Mycoplasma gallisepticum in broiler chicks.
We found that Escherichia coli isolates were resistant against tilmicosin
, tetracycline, ampicillin, amoxicillin with clavulanic acid, ticarcillin, and cephalothin, and contained genes considered responsible for conferring tetracycline resistance.
Unfortunately, some of the other antibiotics tested in this study - such as tilmicosin
and tulathromycin - did show some resistance to the key bacterial pneumonia bugs, so make sure you discuss your treatment protocol with your vet to make sure he or she is confident it will continue to work effectively on your unit should disease break out.
pdf Micotil(R) is a trademark for Elanco's brand of tilmicosin
Most of this book is concerned with the metabolism of veterinary products, not crop protection agents, and it is divided into 16 chapters with titles like Uses and regulation of veterinary drugs - introduction; Veterinary medicines - regulation in Europe and the importance of pharmacokinetic studies; Semduramicin in the chicken - tissue residue depletion studies; Dermal absorption and metabolism of xenobiotics in food-producing animals; Pirlimycin in the diary cow - metabolism and residue studies; Tilmicosin
in cattle - metabolism and tissue residues; Sulphonamide drug in lactating cows - novel metabolism; and Luprositol in dairy cows - residue depletion and metabolism.
Pat James, president of Elanco Animal Health, which assembled the expert panel, noted, "We are extremely pleased that the multidisciplinary expert group did a thorough risk assessment and found that tilmicosin and tylosin can be safely used in pork, poultry, and beef production.
The two macrolide antibiotics included in the study, tylosin and tilmicosin, are used in beef cattle to treat respiratory diseases and to prevent liver abscesses.
Given the low probability of treatment failure as a result of eating meat or poultry from animals treated with these macrolide antibiotics, we concluded that using tylosin and tilmicosin in food animal production has a very low risk to human health," said Dr.
Our risk assessment scientifically addresses questions regarding the potential impact macrolides may have on human health, and shows that current uses of tylosin and tilmicosin in food animals are safe," said lead author H.
experiencing treatment failure due to the acquisition of resistant food-borne bacteria from eating meat or poultry from animals that have been provided or treated with either tylosin or tilmicosin is very low: less than one case in 10 million for resistant Campylobacter and less than one case in 3 billion per year for resistant Enterococcus faecium.
Tylosin and tilmicosin are used in feedlot cattle to treat respiratory diseases and to prevent liver abscesses.