Keywords: Metachromatic leukodystrophy, Motor regression, Tigroid.
T1: affected areas were low signaled while T2: affected areas were high signaled sparing along the venules, with some tigroid pattern (suggestive of metachromatic leukodystrophy) (Figure-2)
Imaging features are pathognomonic, consisting of the well-described tigroid
or folial appearance of alternating superficial bands of hyper- and hypointensity on Tl and T2 weighted imaging within the cerebellar lesion.
Metachromatic leukodystrophy has predominant periventricular white matter involvement with tigroid pattern and spares the subcortical U fibres until late in the disease.
The typical imaging appearance of PMD is nearly complete lack of myelination with tigroid appearance due to sparing of perivascular white matter.
Another common finding is reticular subretinal pigmentation, which is of no pathological significance Some people, with completely healthy eyes, show an interesting striped pigmentation to the fundus, known as a tigroid
Smudged nuclei, tigroid
appearance and RBCs were seen in the background (Figure 1).