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Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
A drug that blocks platelet aggregation, C14H14ClNS, used in its hydrochloride form to prevent stroke and to treat intermittent claudication.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
ticlopidineTherapeutics A platelet aggregation inhibitor that alters the platelet membrane, interfering with membrane-fibrinogen interaction by blocking platelet gpIIb/IIIa receptor Indications ↓ Stroke in high risk Pts, minimize stroke progression, cerebral ischemia, progression of diabetic retinopathy Side effects BM suppression with severe reversible neutropenia, diarrhea, rash, gastritis or gastric ulcers–nausea, dyspepsia, hemorrhage, thrombocytopenia, ↑ cholesterol. See TIA.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
ticlopidineA thienopyridine drug that interacts with platelet glycoprotein in such a way as to inhibit platelet function. It has been found useful in preventing vein grafts from becoming occluded by thrombosis.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005