thyrotropin


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Related to thyrotropin: thyrotropin alpha

thyrotropin

 [thi´ro-tro″pin, thi-rot´rah-pin]
a hormone secreted by the anterior lobe of the pituitary gland that has an affinity for and specifically stimulates the thyroid gland. Called also thyroid-stimulating hormone.
thyrotropin alfa a recombinant form of human thyrotropin; it binds to thyrotropin receptors and stimulates the steps in thyroid hormone synthesis, including iodine uptake and synthesis and secretion of thyroglobulin; used as a diagnostic adjunct in serum thyroglobulin testing, with or without radioiodine scanning, in followup of patients with well-differentiated thyroid cancer, administered intramuscularly.
thyrotropin-releasing hormone stimulation test (thyrotropin-releasing hormone test) a thyroid function test that assesses release of thyrotropin by the pituitary gland; a bolus of thyrotropin-releasing hormone is administered and serum concentrations of thyrotropin are assessed at intervals; if serum levels do not increase within 30 to 40 minutes, the pituitary thyrotrophs are dysfunctional. Called also TRH test and TRH stimulation test.

thy·rot·ro·pin

(thī-rot'rō-pin, thī-rō-trō'pin),
A glycoprotein hormone produced by the anterior lobe of the hypophysis that stimulates the growth and function of the thyroid gland; also used as a diagnostic test to differentiate primary and secondary hypothyroidism.
[for thyrotrophin, fr. thyro- + G. throphē, nourishment; corrupted to -tropin, and reanalyzed as fr. G. tropē, a turning]

thyrotropin

(thī′rə-trō′pĭn, thī-rŏt′rə-) also

thyrotrophin

(-fĭn)
n.
A hormone secreted by the anterior lobe of the pituitary gland that stimulates and regulates the activity of the thyroid gland. Also called thyroid-stimulating hormone, thyrotropic hormone.

thy′ro·tro′pic (-trō′pĭk, -trŏp′ĭk), thy′ro·tro′phic (-trō′fĭk, -trŏf′ĭk) adj.

thyrotropin

Thyroid stimulating hormone. See TSH.

thy·rot·ro·pin

(thī'rō-trō'pin)
A glycoprotein hormone produced by the anterior lobe of the hypophysis that stimulates the growth and function of the thyroid gland; it also is used as a diagnostic test to differentiate primary and secondary hypothyroidism.
Synonym(s): thyroid-stimulating hormone, thyrotrophin.
[fr. thyro- + G. throphē, nourishment; corrupted to -tropin, and reanalyzed as fr. G. tropē, a turning]

Thyroid stimulating hormone (thyrotropin)

A hormone that stimulates the thyroid gland to produce hormones that regulate metabolism.
Mentioned in: Pituitary Dwarfism

thy·rot·ro·pin

(thī'rō-trō'pin)
Glycoprotein hormone produced by anterior lobe of hypophysis; also used as a diagnostic test to differentiate primary and secondary hypothyroidism.
[fr. thyro- + G. throphē, nourishment; corrupted to -tropin, and reanalyzed as fr. G. tropē, a turning]
References in periodicals archive ?
Thus, the present study "Correlation between obesity & thyrotropin (TSH) in clinically euthyroid subjects" was undertaken.
Endogenous thyrotropin and triiodothyronine concentrations in individuals with thyroid cancer.
Rosellini et al., "Sporadic nonautoimmune congenital hyperthyroidism due to a strong activating mutation of the thyrotropin receptor gene," Thyroid, vol.
A novel deletion in the thyrotropin b-subunit gene identified by array comparative genomic hybridization analysis causes central congenital hypothyroidism in a boy originating from Turkey.
Post-transcriptional regulation of the sodium/iodide symporter by thyrotropin. J Biol Chem 2001;276:21458-21463.
Lax et al., "Thyrotropin receptor autoantibodies are independent risk factors for Graves' ophthalmopathy and help to predict severity and outcome of the disease," The Journal of Clinical Endocrinology and Metabolism, vol.
Molecular basis of thyrotropin and thyroid hormone action during implantation and early development.
Spectrum of subclinical and overt hypothyroidism: effect on thyrotropin, prolactin, and thyroid reserve, and metabolic impact on peripheral target tissues.
"Controversy in clinical endocrinology: the evidence for a narrower thyrotropin reference range is competing", J Clin Endocrinol Metab., Vol.90, pp.5483-5488, http://dx.doi.org/10.1210/jc.2005-0455
Potential risks of the adverse effects of thyrotropin suppression in differentiated thyroid carcinoma.
The BMI was calculated with the formula of "BMI = weight (kg)/(height (m))2" Fasting blood samples (12 h overnight fast) were collected at the same time for measurements of fasting blood glucose (FBG), fasting insulin (FINS), glycosylated hemoglobin (HbAlc), triglycerides (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), free triiodothyronine (FT3), free thyroxine (FT4), thyrotropin (TSH), thyroid peroxidase antibody (TPOAb), and thyroglobulin antibody (TGAb).
Thyroid hormone synthesis and secretion are regulated primarily by changes in circulating concentration of pituitary thyrotropin (TSH).

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