thyrotrophin


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thyrotropin

 [thi´ro-tro″pin, thi-rot´rah-pin]
a hormone secreted by the anterior lobe of the pituitary gland that has an affinity for and specifically stimulates the thyroid gland. Called also thyroid-stimulating hormone.
thyrotropin alfa a recombinant form of human thyrotropin; it binds to thyrotropin receptors and stimulates the steps in thyroid hormone synthesis, including iodine uptake and synthesis and secretion of thyroglobulin; used as a diagnostic adjunct in serum thyroglobulin testing, with or without radioiodine scanning, in followup of patients with well-differentiated thyroid cancer, administered intramuscularly.
thyrotropin-releasing hormone stimulation test (thyrotropin-releasing hormone test) a thyroid function test that assesses release of thyrotropin by the pituitary gland; a bolus of thyrotropin-releasing hormone is administered and serum concentrations of thyrotropin are assessed at intervals; if serum levels do not increase within 30 to 40 minutes, the pituitary thyrotrophs are dysfunctional. Called also TRH test and TRH stimulation test.

thy·rot·ro·pin

(thī-rot'rō-pin, thī-rō-trō'pin),
A glycoprotein hormone produced by the anterior lobe of the hypophysis that stimulates the growth and function of the thyroid gland; also used as a diagnostic test to differentiate primary and secondary hypothyroidism.
[for thyrotrophin, fr. thyro- + G. throphē, nourishment; corrupted to -tropin, and reanalyzed as fr. G. tropē, a turning]

thyrotrophin

/thy·ro·troph·in/ (-tro″fin) thyrotropin.

thy·rot·ro·pin

(thī'rō-trō'pin)
A glycoprotein hormone produced by the anterior lobe of the hypophysis that stimulates the growth and function of the thyroid gland; it also is used as a diagnostic test to differentiate primary and secondary hypothyroidism.
Synonym(s): thyroid-stimulating hormone, thyrotrophin.
[fr. thyro- + G. throphē, nourishment; corrupted to -tropin, and reanalyzed as fr. G. tropē, a turning]

thyrotrophin

; thyrotropin thyroid-stimulating hormone (TSH); secreted by anterior pituitary; stimulates thyroid gland growth/function

thyrotrophin

thyrotropin.
References in periodicals archive ?
Primary hypothyroidism is invariably accompanied by increased thyrotrophin secretion.
Snyder PJ, Jacobs LS, Rabello MM, et al: Diagnostic value of thyrotrophin-releasing hormone in pituitary and hypothalamic diseases, assessment of thyrotrophin and prolactin secretion in 100 patients.
Glycoprotein hormones: Glycobiology of gonadotrophins, thyrotrophin and free alpha subunit.
Simultaneous measurement of thyroxine (T4) and thyrotrophin (TSH) from newborn dried blood spot specimens using a multiplexed fluorescent immunoassay.
Analytical and diagnostic accuracy of "second generation" assays for thyrotrophin receptor antibodies with radioactive and chemiluminescent tracers.
Thyrotrophin releasing hormone induced calcitonin secretion in patients with medullary carcinoma of the thyroid.