thyrotrophin


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thyrotropin

 [thi´ro-tro″pin, thi-rot´rah-pin]
a hormone secreted by the anterior lobe of the pituitary gland that has an affinity for and specifically stimulates the thyroid gland. Called also thyroid-stimulating hormone.
thyrotropin alfa a recombinant form of human thyrotropin; it binds to thyrotropin receptors and stimulates the steps in thyroid hormone synthesis, including iodine uptake and synthesis and secretion of thyroglobulin; used as a diagnostic adjunct in serum thyroglobulin testing, with or without radioiodine scanning, in followup of patients with well-differentiated thyroid cancer, administered intramuscularly.
thyrotropin-releasing hormone stimulation test (thyrotropin-releasing hormone test) a thyroid function test that assesses release of thyrotropin by the pituitary gland; a bolus of thyrotropin-releasing hormone is administered and serum concentrations of thyrotropin are assessed at intervals; if serum levels do not increase within 30 to 40 minutes, the pituitary thyrotrophs are dysfunctional. Called also TRH test and TRH stimulation test.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

thy·rot·ro·pin

(thī-rot'rō-pin, thī-rō-trō'pin),
A glycoprotein hormone produced by the anterior lobe of the hypophysis that stimulates the growth and function of the thyroid gland; also used as a diagnostic test to differentiate primary and secondary hypothyroidism.
[for thyrotrophin, fr. thyro- + G. throphē, nourishment; corrupted to -tropin, and reanalyzed as fr. G. tropē, a turning]
Farlex Partner Medical Dictionary © Farlex 2012

thy·rot·ro·pin

(thī'rō-trō'pin)
A glycoprotein hormone produced by the anterior lobe of the hypophysis that stimulates the growth and function of the thyroid gland; it also is used as a diagnostic test to differentiate primary and secondary hypothyroidism.
Synonym(s): thyroid-stimulating hormone, thyrotrophin.
[fr. thyro- + G. throphē, nourishment; corrupted to -tropin, and reanalyzed as fr. G. tropē, a turning]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Thyroid function was assessed by serum free [T.sub.4] ([FT.sub.4], RV = 0.9-1.8 ng/dL), thyrotrophin (TSH, RV = 0.41-4.5 mIU/mL) (enzyme immunoassay kits, GenBio, San Diego, USA).
Plasma thyrotrophin and its response to thyrotrophin releasing hormone in endemic goitre.
Clinical experience with recombinant human thyrotrophin (rhTSH) in the management of patients with differentiated thyroid cancer.
We are unaware of human studies on phthalates and thyroid function; therefore, we designed the present study to investigate potential relations between biological markers of phthalate exposure and levels of [T.sub.4], [T.sub.3], and thyroid-stimulating hormone (thyrotrophin, TSH) in adult men.
Thyroid disease and high concentration of serum thyrotrophin in a population sample of women: A 4-year follow-up.
Although levels of pituitary trophic hormones are generally low in this condition, the thyrotrophin (TSH) was normal in seven cases in the present series.
Premawardhana, "The role of thyrotrophin receptor antibody assays in Graves' disease," Journal of Thyroid Research, vol.
Thyrotrophin and free thyroxine trimester-specific reference intervals in a mixed ethnic pregnant population in the United Arab Emirates.
John, "Potent thyrotrophin receptor-blocking antibodies: a cause of transient congenital hypothyroidism and delayed thyroid development," European Journal of Endocrinology, vol.