It is a 31-33-kDa protein and especially synthesized in the anterior pituitary, and also is limited expression level in thyrotropes
, sommatotropes and lactotropes (Haugen et al.
The thermoregulatory centre, the preoptic area and neurosecretory glands in the hypothalamus along with thyrotropes
in the anterior pituitary gland control all these reactions (Tortora & Grabowski 2003).
The hypothalamus produces TRH, which acts on the pituitary thyrotropes
to stimulate the synthesis and release of TSH.
The TRH, transported by axons, binds to TRH receptors in the pituitary thyrotropes
, a subpopulation of pituitary cells that secrete thyroid-stimulating hormone (TSH).
Board 11 SPERM PROTEIN SP22 IN SOMATOTROPES AND THYROTROPES
Percentage of co-labeled cells differed (P<0.01), with corticotropes = gonadotropes = lactotropes < thyrotropes