1. A hypothetic substance formerly believed to be an abnormal product of diffusely hyperplastic thyroid glands in people with Graves disease, and presumed to cause the distinctive signs and symptoms of that condition (in contrast to simple hyperthyroidism).
2. A complement-fixing antigenic factor associated with certain diseases of the thyroid gland.
3. Rarely used term referring to any material toxic to thyroidal tissue.
a theoretic cytotoxin of the thyroid gland, assumed to be a cause of the signs and symptoms of thyrotoxicosis.
thyrotoxin(1) A name given to both:
• A putative toxic substance produced in the diffusely hyperplastic thyroid gland of Graves’ disease; and
• The various complement-fixing antigens that have been identified as targets in autoimmune thyroiditis.
(2) A rarely used term for any thyrotoxic substance.