thyroid peroxidase


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thyroid peroxidase

thyroid oxidoreductase that catalyzes incorporation of iodide to tyrosine residues in the production of thyroxine, in a process termed organification (q.v.); deficiency of this enzyme leads to a loss of the iodotyrosine derivatives and iiodine from the thyroid and results in goiter.

thyroid peroxidase

thyroid oxidoreductase that catalyzes incorporation of iodide to tyrosine residues in the production of thyroxine, in a process termed organification (q.v.); deficiency of this enzyme leads to a loss of the iodotyrosine derivatives and iiodine from the thyroid and results in goiter.
References in periodicals archive ?
Thyroid status parameters, such as, thyroid stimulating hormone (TSH), free thyroxine (FT4) and thyroid peroxidase antibodies (TPOAb) were measured at the Center for the Scientific and Clinical Study of Endocrinology, Uzbekistan Public Health Ministry.
Minocycline and the thyroid: antithyroid effects of the drug, and the role of thyroid peroxidase in minocycline-induced black pigmentation of the gland.
Objective: The objective of this study was to compare the frequency of anti thyroid peroxidase antibody in patients suffering from vitiligo with healthy control group.
CLINICAL PEARL: Consider ordering thyroid antibodies including thyroglobulin and thyroid peroxidase antibodies.
Test for complete blood count, complete metaboric panel, calcium, phosphorus, fasting glucose, insulin, thyroid-stimulating hormone, and thyroid peroxidase antibodies.
The present study is planned to perform thyroid function test and thyroid peroxidase antibodies in patients with endogenous depression.
Schmutzler et al (8) demonstrated inhibition of iodide uptake and irreversible inactivation of thyroid peroxidase (TPO) in an in vitro study employing rodent tissue thereby indicating interference with thyroid hormone biosynthesis at the level of iodide uptake and organification by genistein, a soy isoflavone.
Clinical measurements included autoantibodies to thyroid peroxidase (TPOAb) and thyroglobulin (TgAb); thyroid function; and a thyroid ultrasound exam.
The thyroid gland uses an enzyme called thyroid peroxidase (TPO) to incorporate iodine into thyroid hormones.
Inactivation of thyroid peroxidase by soy isoflavones, in vitro and in vivo.
8 g/dl), elevation of the Westergren erythrocyte sedimentation rate (80mm/hr), and positive ANA (1:640), anti-Ro/SSA antibodies (815 U/ml) and thyroid peroxidase (TPO) antibodies (2255U/ml).

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