thymus extract

thymus extract

(thahy-muhs) ,


(trade name),


(trade name),

thymus polypeptides

(trade name)


Therapeutic: antiasthmatics
Respiratory infections.Allergic rhinitis.Asthma.Food allergies.


Thymus extract is derived from bovine thymus glands. It induces T-lymphocyte maturation, stimulates T-cell proliferation, enhances mature T-cell function and has indirect effects on macrophages and B-cell functions. It also reduces airway hyperresponsiveness to methacholine in atopic asthma patients.

Therapeutic effects

Improved immune function.
Reduced acute asthma attacks.


Absorption: Unknown
Distribution: Unknown
Metabolism and Excretion: Unknown
Half-life: Unknown

Time/action profile



Contraindicated in: Hypersensitivity.Immunocompromised patients should only use products that are certified pathogen-free to reduce the risk of infection from diseased animal parts.
Use Cautiously in: Pregnancy and lactation.

Adverse Reactions/Side Effects


  • Potential risk of contamination from diseased animal parts.


Avoid use withimmunosuppressants unless products are certified pathogen-free.None.
Oral (Adults) 750 mg/day of crude thymus polypeptide fraction or 120 mg/day of pure thymus polypeptides (thymomodulin).



Nursing implications

Nursing assessment

  • Assess symptoms of cold or allergies related to the purpose thymus extract is being taken.

Potential Nursing Diagnoses

Risk for infection (Indications)


  • Oral: Administer as recommended.

Patient/Family Teaching

  • Discuss with patient purpose for taking thymus extract.
  • Advise patient to notify health care professional of all Rx or OTC medications, vitamins, or herbal products being taken and to consult with health care professional before taking other medications.
  • Advise female patient to notify health care professional if pregnancy is planned or suspected or if breastfeeding.

Evaluation/Desired Outcomes

  • Improvement in symptoms of cold or allergic rhinitis.
References in periodicals archive ?
Some Siberian ginseng and royal jelly will help your vitality,and vitamin E and thymus extract will also help as well as doing great things for your immune system.
The results with Thymosin alpha 1 in the Italian study are similar to results published in Hepatology in 1991 by Mutchnick et al in which six of seven patients with chronic hepatitis B treated with Thymosin alpha 1 or a calf thymus extract containing Thymosin alpha 1 demonstrated loss of the hepatitis B virus.