CRLF2

(redirected from thymic stromal-derived lymphopoietin receptor)

CRLF2

A gene on chromosome Xp22.3 and Yp11.3 that encodes a protein receptor for thymic stromal lymphopoietin (TSLP), which forms a functional complex with TSLP and IL7R and stimulates cell proliferation by activating STAT3 and STAT5, as well as JAK2. It is
implicated in the development of the haematopoietic system.
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