thymic hyperplasia

thymic hyperplasia

A generic term for an increase in size and weight of the thymus, which may be true hyperplasia (e.g., rebound hyperplasia post-chemotherapy) or “pseudohyperplasia”, in which the normal architectural is maintained with a marked increase in germinal centres, often associated with autoimmune disease (in particular myasthenia gravis).
References in periodicals archive ?
We encountered also a case of thymic lipoma and thymic hyperplasia each (Fig.
Also HRCT images were evaluated in the mediastinal window for the presence of thymic hyperplasia (TH) (increased thymic thickness with [greater than or equal to]13 mm), MLNE (MLNE) (increased short-axis diameter with [greater than or equal to]10 mm), pleural or pericardial abnormalities (effusion or thickening).
Contrary to true thymic hyperplasia, thymic lymphoid hyperplasia has diverse types and shapes.
Thymic hyperplasia is defined as an enlarged thymus composed of normal thymic lobules with preserved corticomedullary differentiation [2].
In general there are two types of thymic hyperplasia: true thymic hyperplasia and lymphoid thymic hyperplasia.
First, in the introduction, the authors reported that thymectomy is not therapeutic for thymic hyperplasia. This information is inaccurate because, although myasthenia gravis is an exclusion criterion, Wolfe et al.
Thymic hyperplasia and neoplasia: a review of current concepts.
[13] suggested that thymic hyperplasia is associated with Graves' disease and that thymic TSHR may act as an autoantigen involved in the pathophysiology of Graves' disease.
Berrih-Aknin, "Microarrays reveal distinct gene signatures in the thymus of seropositive and seronegative myasthenia gravis patients and the role of CC chemokine ligand 21 in thymic hyperplasia," Journal of Immunology, vol.
analyzed the qualitative and quantitative values of CT and CS-MRI in differentiating between THA and lymphoid thymic hyperplasia (lTH) among 83 patients with MG.
In light of these pathologic findings as well as the medical history and clinical response to vitamin K and FFP, the final diagnosis for this patient was thymic hemorrhage secondary to vitamin K deficiency, with possible component of thymic hyperplasia. The patient's respiratory distress resolved over a few days and he was discharged home on hospital day #7 with follow-up by his general pediatrician.
The computed tomography scan explores the presence of a thymoma or thymic hyperplasia. Autoimmune thyroid diseases such as Graves' disease and antibody positive thyroid disease were diagnosed on the basis of clinical features, thyroid ultrasonography, and serum thyroxin and related autoantibody levels.