thymectomy


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to thymectomy: transcervical thymectomy

thymus

 [thi´mus]
a ductless gland lying in the upper mediastinum beneath the sternum; it reaches its maximum development during puberty and continues to play an immunologic role throughout life, even though its function declines with age. During the last stages of fetal life and the early neonatal period, the reticular structure of the thymus entraps immature stem cells arising from the bone marrow and circulating in the blood. The thymus preprocesses these cells, causing them to become sensitized and therefore capable of maturing into a specific differentiated type of lymphocyte. After sensitization by the thymus, the cells reenter the blood and are transported to developing lymphoid tissue, where they seed the cells that eventually become T lymphocytes, a type essential to the development of cell-mediated immunity. If the thymus is removed or becomes nonfunctional during fetal life, the lymphoid tissue fails to become seeded with the sensitized lymphocytes and the body's cell-mediated arm of immunity fails to develop. It is this arm of immunity that is mainly responsible for rejection of organ transplants and resistance to intracellular microbial infection, and perhaps plays a role in natural resistance to cancer.
Thymus.

thy·mec·to·my

(thī-mek'tŏ-mē),
Removal of the thymus gland.
[thymus + G. ektomē, excision]

thymectomy

(thī-mĕk′tə-mē)
n. pl. thymecto·mies
Surgical removal of the thymus.

thy·mec·to·my

(thī-mek'tŏ-mē)
Removal of the thymus gland.
[thymus + G. ektomē, excision]
References in periodicals archive ?
This means that adjuvant radiation within 1 month after extended thymectomy might demonstrate a significant advantage to not having adjuvant radiation therapy.
Experience with the "da vinci" robotic system for thymectomy in patients with myasthenia gravis: Report of 33 cases.
Oger, "Thymus in myasthenia gravis: Comparison of CT and pathologic findings and clinical outcome after thymectomy," Radiology, vol.
Balal et al., "Outcomes of total parathyroidectomy with autotransplantation versus subtotal parathyroidectomy with routine addition of thymectomy to both groups: single center experience of secondary hyperparathyroidism," Balkan Medical Journal, vol.
The course of the disease in the patient we presented is interesting because he had MG associated with thymoma and aplastic anemia as a late complication after thymectomy and remission of thymoma including a list of severe immune complications after allogeneic bone marrow transplantation.
Randomized trial of thymectomy in myasthenia gravis.
Thymectomy is mandatory in individuals with thymoma and is recommended as an alternative for non-thymomatous individuals with generalized myasthenia gravis.
In cases where the diagnosis of THA is obvious and an absolute indication for thymectomy is obtained, the most important factor for the surgeon is the radio-clinicopathological data concerning the THA.
Thymectomy usually results in reduction of the severity of myasthenia, although symptoms may persist in most patients.
Here we report two cases of sudden onset of difficult ventilation due to a migrated doublelumen endotracheal tube (DLT) during robotic thymectomy. We highlight the difficulty in readjustment of the migrated DLT during robotic thymectomy with continuing C[O.sub.2] insufflation.
Current therapeutic strategies mainly include acetylcholinesterase inhibitors, immunosuppressive agents, and thymectomy [6].
The current management of MG includes acetylcholinesterase inhibitors, immunomodulatory agents, and thymectomy. Plasma exchange or intravenous immunoglobulins (IVIg) are used for myasthenic crisis [9].