thromboxane B2


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thromboxane B2 (TXB2)

a stable metabolite of thromboxane A2 that has an effect on polymorphonuclear cells and may possess chemotactic activity. It is released during anaphylaxis in laboratory animals. See also thromboxane A2.
References in periodicals archive ?
Trials included those that evaluated the effects of fish oil (which contains EPA and DHA) or EPA alone on levels of prostaglandin E2, thromboxane B2, or leukotriene B4.
sup][4] In these cases, the proposed pathophysiology was as follows: in humans, exogenous epinephrine promotes platelet aggregation by increasing platelet production from thromboxane B2, heightening the sensitivity of platelets to ADP and promoting the thrombin-induced binding of platelets to fibrinogen.
Biomarkers analysed from both urine and plasma samples included cortisol (also analysed from saliva), substance P (SUBP), leukotriene B4 (LTB4), thromboxane B2 (Tbx-B2) and midkine.
This is a rather rare condition, and it should preferably be measured by a specific COX-1 test such as serum thromboxane B2.
The notification was based on the equivalence of TxBCardio to Corgenix's AspirinWorks ELISA urine test, which is authorised by the FDA to gauge levels of 11-dehydro thromboxane B2 (11dhTxB2) to determine aspirin effect in apparently healthy people.
AspirinWorks is a simple, non-invasive lab test performed on a urine specimen, which helps doctors accurately determine aspirin effect in apparently healthy individuals by measuring levels of 11-dehydro thromboxane B2 (11-dhTxB2).
6] (2) It decreases the synthesis of prostaglandin like PGE2 and thromboxane B2 which are responsible for the inflammatory process.
Their healing substances fight and directly block inflammatory compounds like prostaglandin E2, thromboxane B2, interleukin-6 and C-reactive protein.
This results in a decreased synthesis of thromboxane B2 and decreased production of potent vasoconstrictors leukotriene C4 and prostaglandin E2 by platelets (Ali and Mohammed, 1986; Srivastava, 1986; Ali et al.
She explains that the new assay measures levels of 11-dehydro thromboxane B2 which allows platelets to clump and which is secreted in the urine.
Naproxen significantly inhibited platelet aggregation and ex vivo thromboxane B2 synthesis and decreased urinary excretion of prostaglandin E2.
2002), this methoxiflavone has proved to be a LTC4 and thromboxane B2 inhibitor (Skaltsa et al.