Diagnosis: pulmonary tumor thrombotic microangiopathy
developing cor pulmonale.
VEGF inhibition and renal thrombotic microangiopathy
aHUS is a chronic, ultra-rare, and life-threatening disease in which a genetic deficiency in one or more complement regulatory genes causes chronic uncontrolled complement activation, resulting in complement-mediated thrombotic microangiopathy
(TMA), the formation of blood clots in small blood vessels throughout the body.
The clinical pictures were consistent with thrombotic microangiopathy
and are the first reported cases of tiger snake envenomation associated thrombotic microangiopathy
(TMA), which is histologically defined as the development of hyaline thrombi in small vessels, is a frequent finding in patients with thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS).
in malignant hypertension and hemolytic uremic syndrome (HUS)/thrombotic thrombocytopenic purpura (TTP): can we differentiate one from the other?
Consequently, the formation of thrombotic microangiopathy
lesions occurs predominately in renal glomeruli and small renal arterioles.
Nonetheless, no data indicate that anticoagulation is beneficial for thrombotic microangiopathy
, valvular heart disease, livedo reticularis, leg ulcers, or MRI abnormalities associated with cognitive dysfunction.
Detection of the proteolytic enzyme ADAMTS-13 may be used to differentiate between the forms of thrombotic microangiopathy
(TMA), thrombotic thrombocytopenic purpura (TTP) and hemolytic-uremic syndrome (HUS).
Although the typical pathologic lesions of SLE and TTP both primarily involve arterioles, the characteristic histologic patterns are distinct: inflammation with vasculitis in SLE and platelet-rich thrombi without overt inflammation, termed thrombotic microangiopathy
, in TTP.
coli infections: enteropathy, inflammation and vasculopathy, thrombotic microangiopathy
, and nephropathy.
ABANO TERME, ITALY -- Much has been learned about triggering factors and the range of clinical manifestations in catastrophic antiphospholipid syndrome to describe a constellation of events including multiple organ failure, thrombotic microangiopathy
, and tissue necrosis, but the pathogenesis is unclear and mortality remains in excess of 50%, said Dr.