thrombotic microangiopathy


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microangiopathy

 [mi″kro-an″je-op´ah-the]
a disorder involving the small blood vessels. adj., adj microangiopath´ic.
thrombotic microangiopathy formation of thrombi in the arterioles and capillaries; proposed name for a syndrome that would include both thrombotic thrombocytopenic purpura and hemolytic uremic syndrome.

throm·bot·ic mi·cro·an·gi·op·a·thy

thrombosis within small blood vessels, as in thrombotic thrombocytopenic purpura.

thrombotic microangiopathy

the formation of thrombi in the arterioles and capillaries, as occurs in thrombotic thrombocytopenic purpura and hemolytic uremia syndrome.

microangiopathy

a disorder involving the small blood vessels.

cerebrospinal microangiopathy
in pigs is manifested by depression, incoordination, aimless wandering, circling and wasting. The characteristic microangiopathy is not restricted to the nervous system. Thought to be a sequel to chronic edema disease.
dietetic microangiopathy
one of the less commonly occurring lesions that can be prevented by the dietary addition of selenium and vitamin E.
thrombotic microangiopathy
formation of thrombi in the arterioles and capillaries.
References in periodicals archive ?
Early clinical indicators of transplant-associated thrombotic microangiopathy in pediatric neuroblastoma patients undergoing auto-SCT.
12] deficiency causing a thrombotic microangiopathy with thrombocytopenia and a "pseudo-TTP" syndrome.
Thrombotic microangiopathy in patients with sickle cell syndromes, especially intracardiac thrombi without underlying structural diseases or atrial arrhythmias, is a rare complication.
A syndrome consistent with thrombotic microangiopathy has been described after snakebite for many years, but only recently has the syndrome been recognised as thrombotic microangiopathy.
Thrombotic microangiopathy (TMA), which is histologically defined as the development of hyaline thrombi in small vessels, is a frequent finding in patients with thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS).
The fibrinolytic agents streptokinase and urokinase have also been used to treat acute thrombotic microangiopathy with varying success.
Consequently, the formation of thrombotic microangiopathy lesions occurs predominately in renal glomeruli and small renal arterioles.
Thrombotic microangiopathy is an uncommon but devastating manifestation of long-standing APS.
1-5) Our patient suffered from both diseases, as evidenced by histological analyses: cortical necrosis and signs of thrombotic microangiopathy (fibrin-platelet thrombus material within the glomerular capillary lumina) and abnormal clotting parameters with low fibrinogen, high D-dimer levels and low platelet counts.