Jain D, Nand N, Verma P Saxena D, Jain P Plasmodium Vivax Malaria Causing Cardiomyopathy and Thrombotic Microangiopathy
: A Rare Association.
The long term consequences of thrombotic microangiopathy
Toxicity-mediated dose-dependent thrombotic microangiopathy
may develop due to chemotherapeutic agents such as gemcitabine (acting as an antigen itself); immunosuppressive agents such as cyclosporine and tacrolimus; and growth factor inhibitors such as sirolimus, bevacizumab, and cetuximab (1-3).
Unagami et al., "Two cases of kidney transplantation-associated thrombotic microangiopathy
successfully treated with eculizumab," Nephrology, vol.
In addition, MTORi may cause anemia and thrombocytopenia indirectly by causing thrombotic microangiopathy
. Both everolimus [98-100] and sirolimus [101, 102] have been shown to cause thrombotic microangiopathy
Kamar et al., "Complement mutation-associated de novo thrombotic microangiopathy
following kidney transplantation," American Journal of Transplantation, vol.
There was no evidence of glomerulitis, vasculitis, or thrombotic microangiopathy
. (b) The higher magnification photomicrograph (right, 600x) shows that the interstitial inflammatory cells comprised frequent eosinophils (arrows) as well as lymphocytes and fewer plasma cells.
In 1940, Kasabach and Merritt reported the case of an infant with a capillary hemangioma associated with extensive purpura responsible for thrombocytopenia, thrombotic microangiopathy
and consumption coagulopathy .
Hemolytic uremic syndrome, thrombotic thrombocytopenic purpura, and other thrombotic microangiopathy
. In: JennetteJC, Olson JL, Schwartz MM, Silva FG, eds.
aHUS is a thrombotic microangiopathy
caused by mutations of factor H, factor I, factor B, membrane cofactor protein, C3 convertase component, and thrombomodulin gene.
Altogether, these data suggest that ST2 is a marker of cause of death beyond just GVHD-induced NRM and that the most validated endpoint is 6m-NRM that includes deaths from aGVHD grades III-IV, therapy-resistant GVHD that initially presents as grades I--II, and other severe complications favored by alloreactivity such as sinusoidal obstruction syndrome, thrombotic microangiopathy
, or idiopathic pneumonia syndrome.
Injection abuse of reformulated Opana has been associated with a serious outbreak of HIV and hepatitis C, as well as cases of a serious blood disorder (thrombotic microangiopathy