thrombophilia


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Related to thrombophilia: MTHFR

thrombophilia

 [throm″bo-fil´e-ah]
a tendency toward thrombosis.

throm·bo·phil·i·a

(throm'bō-fil'ē-ă), [MIM*188050]
A disorder of the hemopoietic system in which there is a tendency to the occurrence of thrombosis.
[thrombo- + G. philos, fond]

throm·bo·phil·i·a

(throm'bō-fil'ē-ă)
A disorder of the hemopoietic system in which there is a tendency toward thrombosis.
[thrombo- + G. philos, fond]

thrombophilia

A tendency to blood clotting within the blood vessels (a hypercoagulable state). The condition, which may be of genetic origin results from any defect or deficiency of a natural anticoagulant such as activated protein C, antithrombin or protein S. Resistance to activated protein C is an important cause. Thrombophilia increases the probability of heart attacks, strokes and, in pregnant women, miscarriage.
References in periodicals archive ?
The company said the cobas Factor II and Factor V test enables laboratories to simultaneously assess Factor II and Factor V gene mutations from a single patient sample, which can reduce hands-on time when testing patients for inherited thrombophilia.
Mendez-Huerta et al., "Primary thrombophilia in Mexico XII: Miscarriages are more frequent in people with sticky platelet syndrome," Turkish Journal of Hematology, vol.
Abnormal thrombophilia profile in moyamoya disease is reported in the literature.
Thrombophilia is not routinely tested in cirrhotic patients; however, four patients with cirrhosis were tested for thrombophilia and were found to show protein C and S deficiency, which was expected due to an underlying acquired metabolic synthetic deficiency.
Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): a multinational open-label randomised trial.
Fontcuberta, "Laboratory evaluation and clinical characteristics of 2,132 consecutive unselected patients with venous thromboembolism--results of the Spanish multicentric study on thrombophilia (EMET-Study)," Thrombosis and Haemostasis, vol.
Prothrombin gene mutation is the second most common inherited thrombophilia with a prevalence of approximately 2% [5].
In these cases, congenital or acquired thrombophilia and malignancy should be suspected.
The final diagnosis was acute massive pulmonary embolism, moderate to severe pulmonary arterial hypertension, deep venous thrombosis of the right lower limb and thrombophilia.
There was no previous history and family history of thrombosis or thrombophilia. On general examination she was stable.
Pregnancy is a normal physiological hypercoagulable state which may be exaggerated by underlying thrombophilia. This condition may cause the complications during pregnancy.4 Recently thrombophilia has been suggested as a possible cause of RPL.