thrombopenia


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

thrombocytopenia

 [throm″bo-si″to-pe´ne-ah]
decrease in number of platelets in circulating blood; it can result from decreased or defective platelet production or from accelerated platelet destruction. Conditions related to defective production include hypoplastic or aplastic anemia, infiltration of bone marrow by malignant cells or myelofibrosis, viral infections, nutritional deficiency, and thrombocytopenic purpura. Increased destruction of platelets can be caused by infections, certain drugs, transfusion-related purpuras, idiopathic thrombocytopenic purpura, and disseminated intravascular coagulation. adj., adj thrombocytope´nic.
Patient Care. A major concern is prevention of excessive bleeding from trauma to the mucous membranes, skin, and underlying tissues. All injection and puncture sites, whether from intramuscular, subcutaneous, or intravenous administrations or from bone marrow aspiration and other tests, are carefully monitored for signs of bleeding. These procedures should be coordinated and scheduled so that the number of times the skin is broken is kept to an absolute minimum. If, after withdrawal of a needle or catheter, there is evidence that normal clotting is not taking place, pressure is applied immediately and maintained for 10 to 15 minutes.



Because of the potential for trauma to the rectal mucosa, body temperature should not be taken rectally. Blood pressure cuffs, tourniquets for venipuncture, and similar devices must be used with caution. Hence all persons involved with direct patient care should be apprised of the need for special precautions. When used, antiembolic stockings must be thigh-high, never knee-high.

Patients with a chronic deficit of platelets will need instruction in self-care to avoid inadvertent trauma and irritation. For example, to protect the oral mucosa, a soft toothbrush must be used; dental floss, toothpicks, and other items likely to irritate or cause a break in the mucosa should be avoided. Patients are taught to keep their lips and nasal membranes soft and moist, possibly with KY jelly or some other water-soluble lubricant. An oral intake of fluids above the usual maintenance level is encouraged.

To protect the gastrointestinal mucosa, patients are warned to avoid constipation, extremely rough and hard-to-digest foods such as peanuts and popcorn, and aspirin, steroids, and other drugs known to be irritants. Aspirin, in addition to causing gastrointestinal irritation, also interferes with platelet function.

throm·bo·cy·to·pe·ni·a

(throm'bō-sī'tō-pē'nē-ă),
A condition in which an abnormally small number of platelets is present in the circulating blood.
Synonym(s): thrombopenia
[thrombocyte + G. penia, poverty]

throm·bo·cy·to·pe·ni·a

(throm'bō-sī'tō-pē'nē-ă)
A condition in which there is a decreased number of platelets in the circulating blood.
Synonym(s): thrombopenia.
[thrombocyte + G. penia, poverty]
References in periodicals archive ?
This immunologic test aggregated with clinical and paraclinical investigations sustained positive diagnosis of systemic lupus erythematous associated with lupus nephritis, liver cytolysis, anemia, leukopenia with lymphopenia, thrombopenia.
This synergism could allow to decrease the administered doses of sirolimus in transplant recipients or in patients with autoimmune diseases and thereby lowering the numerous side effects of sirolimus like hypercholesterolaemia, hypertriglyceridaemia, thrombopenia, leukopenia, and anemia.
(66) However, the side effect profile of this combination is significantly greater that pegylated interferon/ribavirin alone: anemia, nausea, diarrhea, chills, irritability, metallic taste in mouth, vomiting, fatigue, hair Joss, neutropenia, thrombopenia, pruritis, and rashes.
Surgery in patients with neutropenia, thrombopenia and sepsis who present with an acute abdomen is however associated with a high mortality.
Reasons for termination of antiviral therapy in intravenous drug users Case Sex Age Time of HCV-PCR Reason for termination termination 3rd month of therapy 1 Male 26 1st month THC+IF--induced psychosis (hospitalization) 2 Male 43 1st month Thrombopenia 3 Male 27 7st month Unknown.
Thrombopenia is typically seen in alcoholic patients and severe forms of pancreatitis.