thrombolytic agent


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Related to thrombolytic agent: Clot busting

thrombolytic agent

Clot-dissolving drug, thrombolytic An agent–eg, tPA, streptokinase, that effects thrombolysis and restores vascular patency–eg, in managing acute MIs. See Thrombolytic therapy, tPA.

thrombolytic agent

Any drug that degrades blood clots. Examples include streptokinase, tenecteplase, tissue plasminogen activator, and urokinase. Such drugs are used to treat the abnormal blood clotting that occurs in heart attacks, some strokes, and pulmonary emboli. They are informally called “clot busters.”

CAUTION!

Thrombolytic drugs should not be given to patients with active bleeding, a history of surgery or major trauma within the preceding two weeks, a brain tumor, or other known risks for intracerebral hemorrhage.
See also: agent
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References in periodicals archive ?
Similar to these two large studies of comparing the efficacy of thrombolytics in patients of AMI, reported that there were no significant differences in 30-35 days mortality with three thrombolytic agents, i.
Effectiveness and comparison of reteplase versus streptokinase thrombolytic agents in the patients of acute myocardial infarction
Although the current availability of new generation thrombolytic agent rt-PA, urokinase remained the dominant agent for its general acceptance and low price.
Safety and Efficacy of Low Dosage of Urokinase for Catheter-directed Thrombolysis of Deep Venous Thrombosis
If bleeding cannot be controlled, stop infusion of thrombolytic agent and inform the health care provider immediately.
Circulation savers: thrombolytic therapy
No controlled trials have compared the different thrombolytic agents.
Upper extremity D.V.T: a review article
In addition, among up-to-date thrombolytic agents approved by health authorities only intravenous recombinant tissue plasminogen activator (rt-PA) is used as a systemic one.
Efficacy and safety of intra-arterial thrombolytic therapy for ischemic stroke
We believe the routine use of a thrombolytic agent on clotted blood and bone marrow specimens should become standard for all cytogenetics laboratories.
Application of thrombolytic drugs on clotted blood and bone marrow specimens to generate usable cells for cytogenetic analyses
No thrombolytic agent is currently on the market that has been FDA-approved in HD catheter management.
A practical review of the kidney dialysis outcomes quality initiative (KDOQI) guidelines for hemodialysis catheters and their potential impact on patient care
Acute aortic thromboembolism has been treated either by conservative methods such as supportive care and antithrombotics or by surgical thrombolectomy or administration of thrombolytic agents.
Blood clots in cats with heart disease
The thrombolytic agent is administered via the multiple side-hole catheter using a starting dose of 10 mg rtPA dissolved in 100 ml of a heparin saline solution injected over half an hour using a 'pulse spray technique'.
Thrombolysis for deep venous thrombosis
Fibrinolytic or thrombolytic agents convert plasminogen to plasmin, lyse the clot by breaking down the fibrin contained in a clot.
Production & purification of a fibrinolytic enzyme (thrombinase) from Bacillus sphaericus
Based on my and the company's significant experience in the field of thrombolytic agents, I am optimistic that microplasmin could represent a major advance in the treatment of this very important disease.
THROMBOGENICS STARTS PHASE IIA OF MICROPLASMIN FOR STROKE
However, the hospitals could not agree on which type of thrombolytic agent to use.
Cash row 'puts lives at risk

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