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Related to thrombolytic agent: Clot busting
thrombolytic agentClot-dissolving drug, thrombolytic An agent–eg, tPA, streptokinase, that effects thrombolysis and restores vascular patency–eg, in managing acute MIs. See Thrombolytic therapy, tPA.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
Any drug that degrades blood clots. Examples include streptokinase, tenecteplase, tissue plasminogen activator, and urokinase. Such drugs are used to treat the abnormal blood clotting that occurs in heart attacks, some strokes, and pulmonary emboli. They are informally called “clot busters.”
CAUTION!Thrombolytic drugs should not be given to patients with active bleeding, a history of surgery or major trauma within the preceding two weeks, a brain tumor, or other known risks for intracerebral hemorrhage.
See also: agent
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