Despite increasing evidence that LOX-1, a cell-surface receptor for oxLDL, is implicated in thrombogenesis
and atherogenesis, its involvement in the regulation of TF expression in macrophages remains unclear.
Therefore, overall effect of simvastatin beyond lowering cholesterol includes improving endothelial function, modulating thrombogenesis
, attenuating inflammatory, and oxidative stress damage, and facilitating angiogenesis .
Vascular Gas6 contributes to thrombogenesis
and promotes tissue factor upregulation after vessel injury in mice.
Differential effects of alpha- and gamma-tocopherol on low-density lipoprotein oxidation, superoxide activity, platelet aggregation and arterial thrombogenesis
. J Am Coll Cardiol.
Increased von Willebrand factor in the endocardium asa local predisposing factor for thrombogenesis
in overloaded human atrial appendage.
Platelets also have a very important role in hemostasis and thrombogenesis
. Platelet is a catalyzing coagulation reaction agent, which leads to the formation of fibrin, but does not react negatively with other blood cells .
Moeslinger, "ATP-sensitive potassium channels expressed by human monocytes play a role in stasis-induced thrombogenesis
via tissue factor pathway," Life Sciences, vol.
Lip, "Atrial fibrillation, arrhythmia burden and thrombogenesis
," International Journal of Cardiology, vol.
5-HT, induced by impaired vascular endothelial cells, is involved in the pathological process of platelet aggregation , thrombogenesis
, contraction of carotid arteries , and arteriogenesis  in DM-induced vascular complications through 5-H[T.sub.2A]R.
Tumor cells express tissue factors that activate the clotting cascade, tumor procoagulants, fibrinolytic proteins and receptors for these factors, promoting interactions between the tumor cells, platelets and endothelial cells via cytokines, tumor antigens, and their immune complexes to facilitate thrombogenesis
However, evidence has shown that platelet microparticles (PMP) have a major role in thrombogenesis
It is possible that treating eosinophilia removed the driving factor of thrombogenesis
and subsequently led to rapid thrombolysis.