thrombogen

pro·throm·bin

(prō-throm'bin),

A glycoprotein, molecular weight approximately 72,500, formed and stored in the parenchymal cells of the liver and present in blood in a concentration of approximately 20 mg/100 mL. In the presence of thromboplastin and calcium ion, prothrombin is converted to thrombin, which in turn converts fibrinogen to fibrin, this process resulting in coagulation of blood; a deficiency of prothrombin leads to impaired blood coagulation.

Synonym(s): serozyme, thrombinogen, thrombogen

pro·throm·bin

(prō-throm'bin)

A glycoprotein, formed and stored in the parenchymal cells of the liver and present in blood in a concentration of approximately 20 mg/100 mL; deficiency leads to impaired blood coagulation.