thrombocythaemia type 1(redirected from thrombocytosis 1)
thrombocythaemia type 1A myeloproliferative disorder (OMIM:187950) characterised by increased platelets due to sustained proliferation of megakaryocytes, often leading to thrombosis and haemorrhage.
Caused by defects of THPO, which encodes thrombopoietin, a humoral growth factor required for megakaryocyte proliferation and maturation.
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