thrombocythaemia


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thrombocythaemia

An abnormally high number of blood PLATELETS and megakaryocytes. There is an abnormal tendency to THROMBOSIS, but also to bleeding. The platelet number can be reduced by chemotherapy or radioactive phosphorus.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
A total of 93 subjects with classical myeloproliferative neoplasms were evaluated in the study, 33(35%) of them were polycythaemia vera, 36 (39%) were essential thrombocythaemia and 24 (26%) were having idiopathic myelofibrosis.
AESSENTIAL thrombocythaemia is a rare condition in which cell fragments in the blood (platelets, which help clotting) increase in numbers to over 1000 x 109 /L - around three times higher than normal.
This report provides comprehensive information on the therapeutic development for Thrombocythaemia Myelofibrosis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
[USPRwire, Mon Dec 08 2014] Global Markets Direct's, 'Thrombocythaemia Myelofibrosis - Pipeline Review, H2 2014', provides an overview of the Thrombocythaemia Myelofibrosis's therapeutic pipeline.
Histomorphometry of bone marrow biopsies in chronic myeloproliferative disorders with associated thrombocytosis-features of significance for the diagnosis of primary (essential) thrombocythaemia. Virchows Arch A Pathol Anat Histopathol.
Fischer T, Kirkpatrick The Incidence of Myelofibrosis in Essential Thrombocythaemia, Polycythaemia vera and Chronic Idiopathic Myelofibrosis: A Retrospective Evaluation of Sequential Bone Marrow Biopsies.
Serum erythropoietin values in erythrocytoses and in primary thrombocythaemia. Br J Haematol 2002;117:47-53.
Increased risk for vascular complications in PRV-1 positive patients with essential thrombocythaemia. Br J Haematol 2003;123:513-6.
Thrombosis and haemorrhage in polycythaemia vera and essential thrombocythaemia. Br J Haematol 2005;128:275-90.
Impact of endogenous thrombopoietin levels on the differential diagnosis of essential thrombocythaemia and reactive thrombocytosis.