megakaryocyte

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megakaryocyte

 [meg″ah-kar´e-o-sīt″]
the giant cell of bone marrow; it is a large cell with a greatly lobulated nucleus, and is generally supposed to give rise to blood platelets.

meg·a·kar·y·o·cyte

(meg'ă-kar'ē-ō-sīt),
A large cell (as much as 100 mcm in diameter) with a polyploid nucleus that is usually multilobed; megakaryocytes are normally present in bone marrow, not in the circulating blood, and give rise to blood platelets.
[mega- + G. karyon, nut (nucleus), + kytos, hollow vessel (cell)]

megakaryocyte

(mĕg′ə-kăr′ē-ō-sīt′, -ə-sīt′)
n.
A large bone marrow cell with a lobulate nucleus that gives rise to blood platelets.

megakaryocyte

A very large cell native to the bone marrow which is the precursor of platelets and the largest (40–100 µm in diameter) normal nucleated haematopoietic cell in the marrow. Megakaryocytes may be relatively small (micromegakaryocytes) and measure 15–30 µm in diameter. The nucleus usually has multiple (8, 16 or 32) overlapping lobes; megakaryocytes with few (2 or 4) lobes may occur in myelodysplasia. Nucleoli are absent, chromatin is coarse, cytoplasm is abundant, stains light blue or pink, and contains numerous purplish-red or pink granules. The N:C ratio is 1:1 to 1:2. Megakaryocytes producing platelets may reveal demarcated granular clumps of platelets extruding/streaming from the margins (platelet budding).

meg·a·kar·y·o·cyte

(meg'ă-kar'ē-ō-sīt)
A large cell with a multilobed nucleus; normally present in bone marrow, not in the circulating blood; gives rise to blood platelets (thrombocytes).
Synonym(s): megalokaryocyte.
[mega- + G. karyon, nut (nucleus), + kytos, hollow vessel (cell)]
Enlarge picture
MEGAKARYOCYTE: (Orig. mag. ×640)
Enlarge picture
MEGAKARYOCYTE

megakaryocyte

(meg?a-kar'e-o-sit?) [? + karyon, nucleus, + kytos, cell]
Large bone marrow cell with large or multiple nuclei from which platelets are derived.
See: platelet; illustrationillustration

megakaryocyte

An unusually large bone marrow cell that releases many small fragments of its CYTOPLASM as the blood PLATELETS essential for clotting (blood coagulation).

Megakaryocyte

A large bone marrow cell with a lobed nucleus that is the precursor cell of blood platelets.