thrifty phenotype


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thrifty phenotype

An “anaemic” body type that results from malnutrition during foetal and early postnatal life, leading to insulin resistance and metabolic dysfunction as adults.
References in periodicals archive ?
The thrifty phenotype theory: This one exists in several forms.
This adaptive mechanism is known as Barker's thrifty phenotype hypothesis.
According to the thrifty phenotype hypothesis, nutritional deprivation early in life gives rise to adaptive mechanisms that could result in greater susceptibility to obesity in adult life (7).
Type 2 (non-insuli-ndependent) diabetes mellitus: the thrifty phenotype hypothesis.
Implications of the thrifty phenotype hypothesis for the health of societies undergoing acculturation--lessons for South African health planning.
Type 2 (non-insulin dependent) diabetes mellitus: the thrifty phenotype hypothesis.
The thrifty phenotype as an adaptive maternal effect.
But in broad outline, the thrifty phenotype hypothesis holds that in periods of nutritional deprivation, the fetus adopts two strategies to ensure survival: It preferentially shunts blood to the brain from key bodily organs; and during a critical window of intrauterine development it engages in programming of organ structure and function so as to maintain long-term metabolic thriftiness later in life under conditions of poor postnatal nutrition.
Today these IUGR fetuses typically enter a world of relative plenty in which their thrifty phenotype causes bodily harm, Dr.
There is another interesting theory called the thrifty phenotype.