third-generation cephalosporin


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third-generation cephalosporin

Any of a group of cephalosporin antibiotics capable of killing aerobic gram-negative rods. They are used to treat pneumonia and meningitis. Some agents, i.e., ceftazidime and cefoperazone, are very effective against against Pseudomonas aeruginosa Examples of third-generation cephalosporins are cefsulodin, cefotaxime, ceftizoxime, ceftriaxone, cefoperazone, moxalactam, and ceftazidime.
See also: cephalosporin
References in periodicals archive ?
coli are resistant to third-generation cephalosporins (1,2).
We start our patients on a combination of a third-generation cephalosporin, penicillin or cloxacillin, an aminoglycoside, and either clindamycin or metronidazole.
Because the strain reported here was already resistant to a third-generation cephalosporin, i.
Considering the higher eradication rates of GABHS with cephalosporins compared with those of penicillin/amoxicillin and the ability of cephalosporins to spare protective organisms, choosing a third-generation cephalosporin after amoxicillin failure was an appropriate and effective treatment decision.
Vancomycin and a third-generation cephalosporin are commonly indicated in initial empiric therapy for bacterial meningitis because of the increasing prevalence of resistant gram-positive bacteria.
Treat presumptive bacterial meningitis with vancomycin and a third-generation cephalosporin such as cefotaxime or ceftriaxone.
Because of the high prevalence of penicillin-resistant pneumococci, it is reasonable to initiate an intravenous third-generation cephalosporin (e.
One particularly encouraging set of statistics involves use of a costly third-generation cephalosporin.
CEDAX([R]), an oral third-generation cephalosporin, was originally discovered by Shionogi and Co.
It consists of ceftazidime, a third-generation cephalosporin, that is an established and respected treatment for serious Gram-negative bacterial infections, and avibactam, a non-?
She recommended single coverage with third-generation cephalosporin in febrile, nontoxic infants and that clinicians consider S.
It has been hypothesized that use of ceftio-fur, a third-generation cephalosporin licensed in the United States for use in cattle, could have selected for Newport MDR-AmpC (2-4, 7).

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