Borderline and schizotypal personality disorders treated with low-dose thiothixene versus placebo.
Goldberg Randomized Low dose thiothixene superior et al.
There is no clear evidence that typical antipsychotics, such as haloperidol (Haldol), thioridazine (Mellaril), thiothixene
(Navane), and chlorpromazine (Thorazine) were useful for treating any neuropsychiatric symptoms.
Lower dosage or avoid use Perphenazine Phenothiazines are contraindicated with significant hepatic impairment Thiothixene
Specific guidelines not available.
Amoxicillin-clavulanate * Augmentin Carbamazepine * Tegretol Chlorpromazine * Thorazine Ciprofloxacin * Cipro Citalopram * Celexa Donepezil * Aricept Galantamine * Reminyl Haloperidol * Haldol Levofloxacin * Levaquin Memantine * Namenda Olanzapine * Zyprexa Risperidone * Risperdal Rivastigmine * Exelon Thioridazine * Mellaril Thiothixene
* Navane Valproate * Depakote
Her medications are ziprasidone, 20 mg/d, thiothixene
, 10 mg/d, benztropine, 3 mg/d, and escitalopram, 30 mg/d.
Response of borderline and schizotypal patients to small doses of thiothixene
She had previous trials of several antipsychotics, including quetiapine, thiothixene
, thioridazine, trifluoperazine, chlorpromazine, and haloperidol, all of which were ineffective and poorly tolerated because of serious side effects.
In these select few--who also had not responded to antidepressants or mood stabilizers--I have found thiothixene
to be especially helpful to rapidly reduce anger.
The first generation antipsychotic medications (FGAs), also commonly referred to as "neuroleptics," which include phenothiazines, butyrophenones, and thiothixenes
, treat many of the symptoms of psychosis but have undesirable side effects such as akathisia, tardive dyskinesia, dystonia, and parkinsonism, collectively referred to as "extrapyramidal side effects" (EPS).