The synthesized acid hydrazide is treated with different substituted phenyl isothiocyanates (a-h) to yield 1-(4-fluorophenyl)-1,3-dihydroisobenzofuran 5- acyl
thiosemicarbazides 11(a-h).
Thiohydrazide ligands have the basic structural unit of -C(=S)-NH-N[H.sub.2] and can function as excellent N,S donor bidentate chelating ligands like
thiosemicarbazides or thiosemicarbazones; however, they have simpler structures as they do not contain [N.sup.4] nitrogen.
More, "Synthesis, docking and invitro screening of mannich bases of
thiosemicarbazide for antifungal activity," Arabian Journal of Chemistry, 2013.
The reaction is shown for
thiosemicarbazide in Scheme 3.
(13.) Moussa, MN, Fouda, AS, Taha, FI, Elnenaa, A, "Some
Thiosemicarbazide Derivatives as Corrosion Inhibitors for Aluminium in Sodium Hydroxide Solution." Bull Korean Chem.
This work will present the synthesis and [.sup.1]HNMR characterization of alloxan tertbntyl thiosemicarbazone and then compare to our series of alloxan
thiosemicarbazide (All-TSC) ligands.
Estimation of serum Urea: Urea reacts with hot acidic Diacetylmonoxime in the presence of
Thiosemicarbazide and produces a rose-purple coloured complex, which is determined colorimetrically [26].
In this research, we synthesized 3-thiosemicarbazone, N(4)-ethyl-3-thiosemicarbazone, N(4)-phenyl-3-thiosemicarbazone of benzophenone by using benzophenone and corresponding
thiosemicarbazide in a 1:1 molar ratio in ethanol.
It has been shown (Domiano et al 1969) that the
thiosemicarbazide molecule itself exist in the transcafiguration as in Fig(Ia) and when complexing in this configuration it behaves as a monohydrate ligand, bonding only through the Sulphur atom.
After routine histological methods, 5 [micro]m sections were obtained and coloured by Gomori's trichrome, periodic acid-Schiff (PAS), Alcian Blue pH 2.5 and pH1.0, acetylation + PAS, acetylation + deacetylation + PAS, acid hydrolysis + PAS, phenylhydrazine + PAS and
thiosemicarbazide + PAS.
2, [IV]) and
thiosemicarbazide [V] is the most dominant.