thioredoxin reductase

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thi·o·re·dox·in re·duc·tase

a flavoprotein that uses NADPH to re-reduce thioredoxin in the formation of deoxyribonucleotides.

PRDX5

A gene on chromosome 11q13 that encodes peroxiredoxin 5, which is involved in intracellular redox signalling. It reduces hydrogen peroxide and alkyl hydroperoxides with reducing equivalents provided in the thioredoxin system.

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ribonucleotide reductase

References in periodicals archive ?

Trx-1 reduces hydrogen peroxide via peroxiredoxin (Prx) and oxidized Trx-1 is reduced by thioredoxin reductase [79].

Hydrogen Sulfide and Cellular Redox Homeostasis

Carrageenan exposure and ROS production inhibited thioredoxin reductase activity and increased oxidation of nucleoredoxin.

The inflammatory effects of Carrageenan--a food additive

The important metabolic functions of Se are supposed to be due to the protection of membrane lipids and macromolecules from oxidative damage by combating against reactive oxygen species; and the activation of antioxidant proteins including glutathione peroxidase, thioredoxin reductase, leading to decreased levels of hydrogen peroxide.

Serum selenium level in patients with gastric non-cardia cancer and functional dyspepsia

The mammalian thioredoxin reductase is a selenoprotein that cannot be produced in bacteria.

Hydrogen sulfide and polysulfides as signaling molecules

They found that for the first time, patients who have SSV within a certain nerval distribution involving skin and eyelashes show the same oxidative stress as observed in the much more frequent general NSV, which is associated with decreased antioxidant capacities including catalase, thioredoxin reductase, and the repair mechanisms methionine sulfoxide reductases.

Graying of hair can now be reversed

mexicana has no genes for glutathione reductase (GR), thioredoxin reductase (TrxR), catalase and selenocysteine-containing glutathione peroxidase which are responsible for intracellular thiol redox homeostasis in mammals (4).

Molecular modeling, structural analysis and identification of ligand binding sites of trypanothione reductase from Leishmania mexicana

We also tested (in vitro, both cellular and chemical) whether Ag ions could inhibit the activity of a key selenoenzyme, thioredoxin reductase (TrxR).

Exposure to silver nanoparticles inhibits selenoprotein synthesis and the activity of thioredoxin reductase

Thioredoxin reductase (TrxR) enzyme activity was determined by measuring the NADPH-dependant reduction of DTNB to TNB.

The toxicity of Aloe barbadensis Miller juice is due to the induction of oxidative stress

In the cytosol, both the thioredoxins and the glutaredoxins are maintained in a reduced state by the action of thioredoxin reductase (TrxB) and glutathione, respectively (21).

Human tissue plasminogen activator expression in Escherichia coil using cytoplasmic and periplasmic cumulative power

The enzymes glutathione peroxidase (b) and thioredoxin reductase (d) are selenium-dependent enzymes and selenoprotein P (c) is the transport protein for selenium.

Iodine

In June, SemBioSys was issued United States Patent 6,750,046 entitled, "Preparation of Thioredoxin and Thioredoxin Reductase Proteins on Oilbodies," and United States Patent 6,753,167 entitled, "Preparation of Heterologous Proteins on Oilbodies.

SemBioSys receives United States patent for vaccine production technology

Selenium confers its antioxidant protection mainly through two enzymes that contain it--glutathione peroxidase and thioredoxin reductase.