thiopurine


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thiopurine

(thī″ŏ-pūr′ēn″) [ thio- + purine]
Any sulfur-containing purine used as an antimetabolite to treat a variety of auotimmune, inflammatory, and neoplastic diseases.
References in periodicals archive ?
The patent at issue involved a method for determining the proper dosage of thiopurine drugs.
Of particular interest is our recently launched CNT Panel, which is highly relevant for patients of East Asian ethnicity who may receive thiopurine drug treatment, prescribed for patients with leukemia in addition to other diseases.
The Mayo claim is a method of optimizing a patient's dosage of a thiopurine drug to treat an autoimmune disorder.
13) Prometheus had been awarded a patent on using thiopurine drugs to treat Crohn's disease.
Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing.
Purinethol (mercaptopurine)###TPMT###with inherited little or no thiopurine S-methyltransferase (TPMT) activity are
In Mayo, the Supreme Court held that the relationships between concentrations of certain metaboalites in the blood and the likelihood that a thiopurine drug dosage will prove ineffective or cause harm are unpatentable laws of nature.
In Mayo, the Supreme Court held that the relationships between concentrations of certain metaboA[degrees]lites in the blood and the likelihood that a thiopurine drug dosage will prove ineffective or cause harm are unpatentable laws of nature.
Patients taking 6-mercaptopurine with xanthine oxidase inhibitors may experience cellular toxicity, as these drugs inhibit the metabolism of 6-mercaptopurine by the enzyme thiopurine methyltransferase, raising its plasma concentration.
Treatment Laboratory medicine is Serum creatinine or selection: being used to estimated glomerular subtype disease filtration rate for populations, with renally excreted important drugs, red cell implications for thiopurine treatment.