thiopentone sodium


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Related to thiopentone sodium: Sodium amytal, Sodium Pentobarbital, Carbenoxolone

thiopentone sodium

Thiopental, a barbiturate drug widely used as a pleasant and rapid induction agent for general anaesthesia. The drug is given by slow intravenous injection. The drug is on the WHO official list. A brand name is Thiopental.
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Thiopentone sodium is one of the most widely drug in the induction of general anesthesia (Krauss and Green, 2000) and it is an ultra-short acting barbiturate, immediately after intravenous injection, thiopental rapidly reaches the CNS, and its effects become apparent within 15-30 sec and duration of anaesthesia is 10-20 min (Andaluz et al., 2012; Goldstein and Aronow, 1960).
A fitting, pregnant (27 weeks), hypertensive (220/11 mmhg), multiparous woman in coma had no further fits following treatment by a thiopentone sodium drip, was conscious after about 17 hours, then was delivered of a dead foetus.
Propofol 3.5 mg/kg in comparison with propofol 2.5 mg/kg and thiopentone sodium 5 mg/kg is effective in reducing the incidence and severity of succinylcholine induced fasciculations and myalgia.
Following induction with thiopentone sodium, there was a fall in systolic and diastolic blood pressure and a slight rise in heart rate in both the groups.
After 10 minutes, 2.5% Thiopentone sodium was administered at dose rate of 25 mg / kg b.
Thiopentone sodium are common intravenous induction agents in our hospital.
Anaesthesia was induced with Thiopentone sodium 2.5% (@10 mg/kg b.wt) and maintained on Isoflurane (1-1.5%) mixed with oxygen.
Comparison of propofol and thiopentone sodium as induction agents for modified electroconvulsive therapy.
Trilfupromazine hydrochloride @ 0.5mg/kg was administrerd intramuscularly as premedicant and anesthesia achieved with Thiopentone sodium @ 20 mg/kg b.