Total
thiol content of the spinal cord was lower for older ages (Figure 7A).
As expected, no significant association was found among the different parameters of Total
thiol, hs-CRP, systolic BP and diastolic BP with retinopathy, as no retinopathy was found among the participants of normal pregnancy.
When the patient and control groups were compared according to the NLR and thiol/disulfide homeostasis parameters, NLR, disulfide/native
thiol and disulfide/total
thiol, the average values were found to be significantly higher (respectively, p<0.001, 0.013 and 0.009) and the native
thiol and total
thiol average values were found to be significantly lower (respectively, p=0.004 and 0.001) in the patient group compared to the control group.
Plasma levels of TDB in the patient and control groups were simultaneously tested via a novel colorimetric method developed by Erel O et al.10 In this method, reducible disulfide bonds (SS) are first reduced to free
thiol groups (SH) using NaBH.
Thiol, which is also known as a mercaptan, contains a hydrogen atom bound to a carbon atom and a sulfur atom, and is a functional group of sulfhydryls [6].
Disulphide levels were lower in the patients compared to the controls (p<0.001).As troponin levels increased, native
thiol, total
thiol and disulphide levels in patients decreased (p1 mm (0.1mV) ST-segment elevation in 2 consecutive leads, and later confirmed by increase in troponin I.
The thiol-disulfide pair tests in the serum were determined using the method by Erel and Neselioglu (11), which is based on the principle of measuring the reduced
thiol groups and existing native
thiols ([micro]mol/L) for the total
thiol ([micro]mol/L) amounts that were analyzed with 5, 5'-dithiobis-(2-nitrobenzoic) acid (DTNB).
Total
thiol molecules were measured spectrophotometrically at 412 nm using 5,5'-Dithiobis(2-nitrobenzoic acid) as the reagent according to the method described by Hu and Dillard.
No correlation was found between the total
thiol level, native
thiol level, and native thiol/total
thiol ratio and significantly increased disulphide level, disulphide/native
thiol, and disulphide/total
thiol ratios levels as analyzed by BMI, lesion duration, disease pattern, and recurrence frequency (p>0.05) (Table 3).
In our study, disulphide levels and the disulphide/native
thiol and disulphide/total
thiol ratios that reflect the OS were found to be higher in the PCOS group than in the non-PCOS group, and native
thiol levels and the native thiol/total
thiol ratio, the markers of the antioxidant system, were observed to be decreased in the PCOS group.
A relationship between a decline in
thiol levels and several systemic diseases has been demonstrated in many studies [14, 15].
We believe this to be the only reported case of skunk
thiol irritant-induced, work-exacerbated asthma.
