content of the spinal cord was lower for older ages (Figure 7A).
As expected, no significant association was found among the different parameters of Total thiol
, hs-CRP, systolic BP and diastolic BP with retinopathy, as no retinopathy was found among the participants of normal pregnancy.
When the patient and control groups were compared according to the NLR and thiol/disulfide homeostasis parameters, NLR, disulfide/native thiol
and disulfide/total thiol
, the average values were found to be significantly higher (respectively, p<0.001, 0.013 and 0.009) and the native thiol
and total thiol
average values were found to be significantly lower (respectively, p=0.004 and 0.001) in the patient group compared to the control group.
Plasma levels of TDB in the patient and control groups were simultaneously tested via a novel colorimetric method developed by Erel O et al.10 In this method, reducible disulfide bonds (SS) are first reduced to free thiol
groups (SH) using NaBH.
, which is also known as a mercaptan, contains a hydrogen atom bound to a carbon atom and a sulfur atom, and is a functional group of sulfhydryls .
Disulphide levels were lower in the patients compared to the controls (p<0.001).As troponin levels increased, native thiol
, total thiol
and disulphide levels in patients decreased (p1 mm (0.1mV) ST-segment elevation in 2 consecutive leads, and later confirmed by increase in troponin I.
The thiol-disulfide pair tests in the serum were determined using the method by Erel and Neselioglu (11), which is based on the principle of measuring the reduced thiol
groups and existing native thiols
([micro]mol/L) for the total thiol
([micro]mol/L) amounts that were analyzed with 5, 5'-dithiobis-(2-nitrobenzoic) acid (DTNB).
molecules were measured spectrophotometrically at 412 nm using 5,5'-Dithiobis(2-nitrobenzoic acid) as the reagent according to the method described by Hu and Dillard.
No correlation was found between the total thiol
level, native thiol
level, and native thiol/total thiol
ratio and significantly increased disulphide level, disulphide/native thiol
, and disulphide/total thiol
ratios levels as analyzed by BMI, lesion duration, disease pattern, and recurrence frequency (p>0.05) (Table 3).
In our study, disulphide levels and the disulphide/native thiol
and disulphide/total thiol
ratios that reflect the OS were found to be higher in the PCOS group than in the non-PCOS group, and native thiol
levels and the native thiol/total thiol
ratio, the markers of the antioxidant system, were observed to be decreased in the PCOS group.
A relationship between a decline in thiol
levels and several systemic diseases has been demonstrated in many studies [14, 15].
We believe this to be the only reported case of skunk thiol
irritant-induced, work-exacerbated asthma.