thiobarbituric acid


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thiobarbituric acid

 [thi″o-bahr″bĭ-tu´rik]
a compound that differs from barbituric acid only by the presence of a sulfur atom instead of an oxygen atom at the number 2 carbon; it is the parent compound of a class of drugs, the thiobarbiturates.
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For the determination of oxidative stress, the most widely acceptable thiobarbituric acid reactive substances assay that quantifies the concentration of malondialdehyde, a product formed as a result of degradation of unstable lipid peroxides [21], was exercised.
Fat oxidation was evaluated by measuring thiobarbituric acid reactive substances (TBARS) [14].
Thiobarbituric acid was added to precipitate at 90[degrees]C for one hour.
Estimation of serum Thiobarbituric acid reacting substances (TBARS) was done following the method described by Okhawa et al.
The method used to determine the levels of thiobarbituric acid reactive substances (TBA-RS) was described by Ohkawa, Ohishi, and Yagi (1979), with slight modifications of De Franceschi et al.
Reaction conditions affecting the relationship between thiobarbituric acid reactivity and lipid peroxides in human plasma.
As an index of lipid peroxidation, the yielding of thiobarbituric acid reactive substances (TBARS) during an acid-heating reaction was determined.
Determination of malonaldehyde precursor in tissues by thiobarbituric acid test.
Serum levels of thiobarbituric acid reactive substances predict cardiovascular events in patients with stable coronary artery disease: a longitudinal analysis of the PREVENT study.
Neutralization of OH radicals, which were generated in a Fenton reaction, was also monitored spectrophotometrically, based on the degradation of 2-deoxy-D-ribose to malondialdehyde (MDA), whereby MDA forms a compound with thiobarbituric acid. The ability of the extract to inhibit generated NO radicals was examined by the use of Griess reagent.
Next, 2 mL of clear filtrate was mixed with 2 mL of 0.02 M aqueous thiobarbituric acid (Sigma-Aldrich, St.
We measured body weight weekly and collected blood and 24-hour urine samples for thiobarbituric acid reactive substances (TBARS), nitric oxide (NO), and glycosuria dosages.