(thī'ō-bar-bi'chū-ritz), Avoid the misspelling/mispronunciation thiobarbituate.
Hypnotics of the barbiturate group, for example, thiopental, in which the oxygen atom at carbon-2 is replaced by sulfur.
References in periodicals archive ?
Barbiturates and thiobarbiturates are medicinally imperative class of heterocyclic compounds as they have been used as antipyretic [1], anticonvulsant [2], antiepileptic agents [3], sedatives, hypnotics [2-5], herbicidal and insecticidal [6], fungicidal [7] and antiviral agents [8].
A convenient way of coupling two medicinally important nucleus (Cyanoactamide and Barbiturates/Thiobarbiturates) via a single pot multicomponent reaction was employed to avail fourteen new cyanoacteamide based barbiturates and thiobarbiturates.
The only well-documented, breed-specific anesthetic drug concern is with the use of thiobarbiturates in Greyhounds," Dr.
A myriad of determinands caught his interest: magnesium, calcium, beryllium, gold, copper, iron, and zinc; phosphorous, chloride, and protein-bound iodine; creatinine, urea, bilirubin, proteins, estrogens, nucleic acids, ketosteroids, and haptoglobin; cholesterol, triglycerides, free fatty acids, and phospholipids; salicylates, barbiturates, thiobarbiturates, methotrexate, carbon monoxide, methanol, and ethanol; alkaline phosphatase, glucose-6-phosphatase, 5-'nucleotidase, cholinesterase, and creatine kinase.
No reports have been found on the interaction of thiobarbiturates with this enzyme.
The concentration of thiopental, a thiobarbiturate, in the plasma of the first boy was 135 mg/L by an HPLC-ultraviolet detection method.
Thiobarbiturates are us ed as anes thetic agents clinically [9].
The discovery and the introduction of thiobarbiturates in intravenous anesthesia made this class of compound potential clinical drugs [1].