thiobarbiturate


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thiobarbiturate

 [thi″o-bahr-bich´er-it]
any of a group of compounds chemically related to barbiturates and with barbituratelike effects.
References in periodicals archive ?
In continuation with our previous research work to develop greener protocols for the synthesis of bioactive heterocyclic compounds [35-36], here we wish to report a convenient method for the synthesis of heteroaryl barbiturates and thiobarbiturates using task-specific ionic liquid 1-butyl-3-methylimidazolium hydroxide [Bmim]OH under neat conditions by using conventional and microwave irradiation technique as shown in (Scheme 1).
According to Dade Behring Japan Ltd., there had been no reports on ammonia assay interference by thiobarbiturates. The mechanism of this interference is not yet clear.
treatment of s chizophrenic patients ; therefore, they are called "s leep cures ." Thiobarbiturates are us ed as anes thetic agents clinically [9].
A myriad of determinands caught his interest: magnesium, calcium, beryllium, gold, copper, iron, and zinc; phosphorous, chloride, and protein-bound iodine; creatinine, urea, bilirubin, proteins, estrogens, nucleic acids, ketosteroids, and haptoglobin; cholesterol, triglycerides, free fatty acids, and phospholipids; salicylates, barbiturates, thiobarbiturates, methotrexate, carbon monoxide, methanol, and ethanol; alkaline phosphatase, glucose-6-phosphatase, 5-'nucleotidase, cholinesterase, and creatine kinase.
Barbiturates and thiobarbiturates are medicinally imperative class of heterocyclic compounds as they have been used as antipyretic [1], anticonvulsant [2], antiepileptic agents [3], sedatives, hypnotics [2-5], herbicidal and insecticidal [6], fungicidal [7] and antiviral agents [8].
Barbiturates played an important role throughout their history: their traditional use as sedative and hypnotic agents, in schizophrenic patients, so-called "sleep cures." The discovery and the introduction of thiobarbiturates in intravenous anesthesia made this class of compound potential clinical drugs [1].