thioamide


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thi·o·am·ide

(thī'ō-am'īd),
An amide in which S replaces O.

thioamide

, thionamide (thī″ō-am′īd″) [ thio- + amide]
Any drug that inhibits the thyroid gland from making thyroid hormone. Examples include methimazole and propylthiouracil.
References in periodicals archive ?
The 13C NMR chemical shifts of thioamide with Pd(II) tris-4-chlorophenyl phosphine complexes are given in the experimental section.
Thiocarbonyl moieties such as thioamide [26-30, 47-53], thiourethane [31, 33, 35, 37], and thiourea [11, 25, 54-60] have also been examined as stable adsorbents.
A solution of ethanebis(thioamide) 0.24 g (2 mmol) and 3,5-di-tert-butyl-2-hydroxybenzaldehyde 0.936 g (4 mmol) in 4 ml of DMF were heated under reflux for 24 h.
K.; Karkabounas, S., Biological studies of new organotin (IV) complexes of thioamide ligands.
[sup.1]H-NMR (300.13 MHz, DMSO-[d.sub.6], [delta] ppm): 4.28 (s, 4H, amine), 9.21 (s, 2H, thioamide), 8.32 (s, 2H, Ar), 7.41 (d, 2H, Ar), 2.31 (d, 4H, OH).
Tholander et al., "Novel thioamide derivatives as neutral CB1 receptor antagonists," Bioorganic & Medicinal Chemistry Letters, vol.
used two different synthetic approaches (i.e., the acylation and thioamidation process on the nitrile groups) to functionalize SWCNTs with AZ via ester or thioamide bonds [34].
Of the samples tested in the first phase, we selected three samples with the lowest value of MIC - N,N-phenyl-1,2,3,4-thiatriazole-5-yl-[beta]-resorcylcarbo- thioamide (PTR), N-3-(1,2,4-dithia-zole-5-thione)[beta]-resorcylcarbothioamide (DTRTA), N,N-phenyl-1,2,3,4-thiatriazol-5-yl-[beta]-resorcylcarbothioamide (PHARA).
The continuation phase with thioamide, ofloxacin (cycloserin) was implemented under clinical conditions.
Our unique design elements are highlighted in this poster and include pharmacophore modification, prodrug utilization, thioamide isosteres, and strategic lipophilicity incorporation.
THIOAMIDE DERIVATIVE MODULATES ANNEXIN V EXPRESSION IN HUMAN LIVER CARCINOMA HEPG2) CELLS 35.