thioamide


Also found in: Wikipedia.

thi·o·am·ide

(thī'ō-am'īd),
An amide in which S replaces O.

thioamide

, thionamide (thī″ō-am′īd″) [ thio- + amide]
Any drug that inhibits the thyroid gland from making thyroid hormone. Examples include methimazole and propylthiouracil.
References in periodicals archive ?
The 13C NMR chemical shifts of thioamide with Pd(II) tris-4-chlorophenyl phosphine complexes are given in the experimental section.
Of the samples tested in the first phase, we selected three samples with the lowest value of MIC - N,N-phenyl-1,2,3,4-thiatriazole-5-yl-[beta]-resorcylcarbo- thioamide (PTR), N-3-(1,2,4-dithia-zole-5-thione)[beta]-resorcylcarbothioamide (DTRTA), N,N-phenyl-1,2,3,4-thiatriazol-5-yl-[beta]-resorcylcarbothioamide (PHARA).
The continuation phase with thioamide, ofloxacin (cycloserin) was implemented under clinical conditions.
Our unique design elements are highlighted in this poster and include pharmacophore modification, prodrug utilization, thioamide isosteres, and strategic lipophilicity incorporation.
THIOAMIDE DERIVATIVE MODULATES ANNEXIN V EXPRESSION IN HUMAN LIVER CARCINOMA HEPG2) CELLS 35.
The structural modifications from previously known antagonists were primarily in the D-ring region, involving a thioamide replacement of an amide.
Compound 4 was subjected to a standard procedure of transforming the cyano group into amidine via thioimidate salt [7], that is nitrile 4 was reacted with hydrogen sulphide affording thioamide 5, which was converted to thioimidate salt 6 with methyl iodide.
The sulfur atom of this compound, which is engaged in a thioamide bond with the indole ring, is responsible for a weak part of the toxicity of Amanita (e.
Metal-thiolate compounds exhibit two thioamide bands appears in the range 1505-1530 cm-1 due to (C=N) stretching vibrations and 1181-1198 cm-1 for (C=S).
The antituberculous activity of thioamide in vitro and in the experimental animal (mouse and guinea pig).