thin melanoma

Stage I cutaneous melanoma A melanoma measuring < 1 cm in diameter, characterized by virtually 100% survival; the prognosis is less favorable if the lesion is > 0.73 mm in thickness–73% 5-yr survival or > 1.5 mm–63% 5-yr survival. See Melanoma.

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Thin melanoma subtyping fits well with the American Joint Committee on Cancer staging system.

A Histogenetic View of the International Classification of Diseases for Oncology Melanomas

It was considered a thin melanoma, which meant the cancer had only gone down into the skin one millimetre.

'I'M DYING because of a dodgy mole on my ankle' Amanda Seymour, 42, is facing incurable stage 4 malignant melanoma, one of the deadliest of all cancers. Reading her story will make you sure to cover yourself in sunscreen this summer

"We are now awaiting publication of a larger analysis of patients with thin melanoma," Dr.

Mitotic rate a game changer in melanoma Tx

Ambulatory narrow excision for thin melanoma (< or = 2 mm): results of a prospective study.

Cutaneous melanoma: detecting it earlier, weighing management options: knowing when and how to biopsy a suspicious lesion is paramount for providing accurate prognosis

Habermann, "The effect of the AJCC 7th edition change in T1 melanoma substaging on national utilization and outcomes of sentinel lymph node biopsy for thin melanoma," Melanoma Research, vol.

Essential Components of Melanoma Histopathological Reporting: The Surgical Oncologist's Perspective

"Sometimes, someone with a thin melanoma lesion will have extensive disease on a PET scan, just as there are patients with a thick melanoma lesion who have ignored it, and they live long."

Sentinel node biopsy may aid melanoma survival: for primary cutaneous melanoma, SLN biopsy appeared to be both predictive and therapeutic

The finding that patients with histologic regression have half the risk for micrometastases in sentinel lymph node biopsy, compared with patients without regression gives a clear answer to the question of whether patients with thin melanoma and regression should undergo SLNB, and that answer is "No."

Regression challenges need for SLNB

Coleman III, "The prognostic importance of sentinel lymph node biopsy in thin melanoma," Annals of Surgical Oncology, vol.

Prediction of sentinel node status and clinical outcome in a melanoma centre

At present, the decision regarding whether to recommend SLNB in a patient with a thin melanoma is based upon a general gestalt, said Dr.

Node results will drive melanoma therapies

Even though patients with early-stage disease (thin melanoma, Breslow depth <1.0 mm) are thought to have an excellent clinical outcome (>85% survival during a 10-year period) (6) and can be treated effectively, 15% of melanoma deaths result from metastases of thin lesions.

Molecular diagnostics in melanoma: current status and perspectives

However, in thin melanomas, thickness does not necessarily discriminate between radial and vertical growth phase.

Thin melanoma

Finally, David Elder, MB, ChB, FRCPA, reviews the literature and work from his laboratory on prognostic modeling in thin melanoma, which is defined as melanoma invasive to less than 1 mm according to Breslow.