thin melanoma

Stage I cutaneous melanoma A melanoma measuring < 1 cm in diameter, characterized by virtually 100% survival; the prognosis is less favorable if the lesion is > 0.73 mm in thickness–73% 5-yr survival or > 1.5 mm–63% 5-yr survival. See Melanoma.

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It was considered a thin melanoma, which meant the cancer had only gone down into the skin one millimetre.

'I'M DYING because of a dodgy mole on my ankle' Amanda Seymour, 42, is facing incurable stage 4 malignant melanoma, one of the deadliest of all cancers. Reading her story will make you sure to cover yourself in sunscreen this summer

We are now awaiting publication of a larger analysis of patients with thin melanoma," Dr.

Mitotic rate a game changer in melanoma Tx

Ambulatory narrow excision for thin melanoma (< or = 2 mm): results of a prospective study.

Cutaneous melanoma: detecting it earlier, weighing management options: knowing when and how to biopsy a suspicious lesion is paramount for providing accurate prognosis

However, in thin melanomas, thickness does not necessarily discriminate between radial and vertical growth phase.

Thin melanoma

Sometimes, someone with a thin melanoma lesion will have extensive disease on a PET scan, just as there are patients with a thick melanoma lesion who have ignored it, and they live long.

Sentinel node biopsy may aid melanoma survival: for primary cutaneous melanoma, SLN biopsy appeared to be both predictive and therapeutic

The finding that patients with histologic regression have half the risk for micrometastases in sentinel lymph node biopsy, compared with patients without regression gives a clear answer to the question of whether patients with thin melanoma and regression should undergo SLNB, and that answer is "No.

Regression challenges need for SLNB

The multivariate models derived from these data can segregate patients with thin melanoma into subgroups whose expected disease-free survival varies from close to 100% to only 70%.

Melanocytic lesions: current state of knowledge--Part II

Age and mitotic rate are continuous variables: the younger the patient and the higher the mitotic rate, the greater the likelihood of a positive SLNB in the setting of a thin melanoma.

Node results will drive melanoma therapies

Importance of sentinel lymph node biopsy in patients with thin melanoma [discussion in Arch Surg.

Sentinel lymph nodes in cutaneous melanoma: handling, examination, and clinical repercussion

Predictive models are being developed that can be used to establish more exacting criteria both for selecting which patients with thin melanomas should undergo SLN biopsy and for identifying those patients with thin melanoma who do not need an SLN biopsy.

Prognostication in thin cutaneous melanomas

Gimotty, PhD, and colleagues at the University of Pennsylvania Pigmented Lesions Clinic, which showed critical predictive value of mitoses and vertical growth phase in thin melanoma.

Melanocytic lesions: current state of knowledge

Anderson patients, the incidence of a sentinel node with metastatic disease was 4% in patients with a thin melanoma that was not ulcerated.

Indications increase for sentinel node biopsy in melanoma dx. (Ulceration, Regression)

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