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a phenothiazine derivative with antihistaminic effects, used in the form of the malate and maleate salts as an antiemetic and antinauseant, particularly to treat nausea and vomiting associated with surgery, chemotherapy, radiation therapy, or toxins; administered orally, rectally, and intramuscularly.
thiethylperazine/thi·eth·yl·per·a·zine/ (thi-eth″il-par´ah-zēn) an antiemetic, used as the malate or maleate salt in the treatment and prophylaxis of nausea and vomiting.
a phenothiazine antiemetic.
indications It is prescribed to control nausea and vomiting.
contraindications Parkinson's disease, central nervous system disorders, liver or renal dysfunction, severe hypotension, or known hypersensitivity to phenothiazine medications prohibits its use.
adverse effects Among the more serious adverse effects are hypotension, liver toxicity, extrapyramidal reactions, blood dyscrasias, and hypersensitivity reactions.
a phenothiazine derivative useful as an antiemetic.