thick filament


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my·o·sin fil·a·ment

one of the contractile elements in skeletal, cardiac, and smooth muscle fibers; in skeletal muscle, the filament is about 15 nm thick and 1.5 mcm long.
Synonym(s): thick filament

thick filament

In a sarcomere, one of the collection of contractile filaments made primarily of myosin, seen microscopically.
References in periodicals archive ?
Ratio of thin filament to the thick filament is more than 1:10 and the mitochondrial area is approximately 25%.
Thin and thick filaments are irregularly mixed in these muscle fibers.
The M-line material in the center of the A band [ILLUSTRATION FOR FIGURE 1 OMITTED] attaches the thick filaments to the basal lamina and thus could also transmit forces to the basal lamina; however, it is unlikely to contribute significantly to the compressive forces acting on the basal lamina.
Thick Filaments. The thick filaments (~16 nm of diameter) are bipolar polymers and the protein myosin is its major component.
Thick filaments in the body wall muscle of the nematode Caenorhabditis elegans have a unique bipolar structure that is composed of myosin A (myoA) and myosin B (myoB) isoforms.
Early dominance by green and brown filaments persisted over 230 d into the experiment, and red filaments (rather than thick filaments and blades) still dominated at the end of the year [ILLUSTRATION FOR FIGURE 4B OMITTED].
When the fiber receives a signal to contract, the thick filaments pull the combs together by "rowing" against the thin filaments.