Nemcova, "Photophysical properties of thiazine
dyes in aqueous solution and in micelles," Dyes and Pigments, vol.
Methylene blue (MB), a thiazine
dye is basically used in the treatment of various methemoglobinaemias.
Several years ago, therefore, Zila filed patent applications in appropriate countries, claiming the use of oxadine and thiazine
classes of dyes in general."
The presence of electron withdrawing groups on the thiazine
dyes slows down the bleaching rates and supports the photosensitizing oxidation process.
Due to its low toxicity and powerful penetration capacity, the thiazine
cationic dye methylene blue is commonly used for lymph nodal vital staining.
Xylazine is a [2-(2 6 dimethyle phenyl amino)-4H-5 5 dihydro-1 3-Thiazine] thiazine
derivative classified as alpha2 adrenergic agonist with sedative analgesic and muscle relaxant properties (Paddleford 1999).
Berridge et al., "Anti-inflammatory thiazine
alkaloids isolated from the New Zealand ascidian Aplidium sp.: inhibitors of the neutrophil respiratory burst in a model of gouty arthritis," Journal of Natural Products, vol.
Methylene blue is a blue, organic cationic thiazine
dye that has been commonly employed as a model dye to evaluate the photocatalytic activity among other photosensitizing dyes like eosin Y, pyrene, and so forth.
"One such development, initially intended for the industrial coatings market but also having utility for screen inks and other opaque ink systems, is our new thiazine
indigo red pigment, Novoperm Till Red 4g 70 VP2543.
Toluidine blue dye is an acidophilic metachromatic dye of the thiazine
The book contains six chapters covering synthesis, reactions and applications in the following subject areas: pyridazines, cinnolines, benzocinnolines and phthalazines; pyrimidines and quinazolines; pyrazines and related ring structures; phenzine, oxazine, thiazine
and sulphur dyes; quinazoline alkaloids; six-membered rings with three or more hetero-atoms.
In the thiazine
ring C8-carbon atom is chiral carbon with R configuration and adopted distorted tetrahedral geometry since the angles around it varies from 104.1(3)Ao to 114.3(3)Ao.