thiamine pyrophosphate


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thiamine pyrophosphate

(thi'a-min, -men? pi?ro-fos'fat?)
An enzyme important in carbohydrate metabolism. It is the active form of thiamine. In people suspected of malnutrition, administering thiamine before the infusion of glucose-containing solutions prevents brain damage (Wernicke-Korsakoff's encephalopathy).
Synonym: cocarboxylase

Thiamine pyrophosphate (TPP)

The coenzyme containing thiamine that is essential in converting glucose to energy.
Mentioned in: Beriberi
References in periodicals archive ?
18 Our results are in conformity with a previous report19 claiming that thiamine pyrophosphate and pyridoxamine inhibit the formation of antigenic AGEs compared with aminoguanidine.
Thiamine and thiamine pyrophosphate, both showed protective effects albeit to different extents.
Thiamine pyrophosphate determination in whole blood and erythrocytes by high performance liquid chromatography.