thiamin deficiency

thiamin deficiency

A vitamin deficiency characterised by malnutrition, softened bones and mental depression, due to an absence of dietary thiamin. The clinical disease, beri-beri, is divided into a “wet” form, which causes congestive heart failure, and a “dry” form, which causes neurologic disease in the form of peripheral neuropathy and Wernicke-Korsakoff syndrome.

thiamin deficiency

Beri-beri Nutrition A vitamin deficiency characterized by malnutrition, softened bones, depression, due to an absence of dietary thiamin; the clinical disease is divided into 'wet' beri-beri, which causes CHF and 'dry' beri-beri, which causes neurologic disease in the form of peripheral neuropathy and Wernicke-Korsakoff syndrome. See Thiamin.

thiamin deficiency (thīˑ··min d·fiˑ·shn·sē),

n insufficient levels of thiamin in the body to support functioning, which causes beriberi.
References in periodicals archive ?
A thiamin deficiency can lead to a condition known as beriberi.
28) In animal studies corticosterone levels have shown to be significantly increased with thiamin deficiency.
If a thiamin deficiency is not detected early, then the patient is at risk of cardiac and neurologic complications that are associated with a thiamin deficiency.
The prevalence of thiamin deficiency in hospitalized patients with congestive heart failure.
Thiamin deficiency has also been associated with outbreaks of PEM.
Chronic high intakes of alcohol predispose to thiamin deficiency in several ways:
Over time a thiamin deficiency can cause damage to several memory-related areas of the brain.
Cobalt depresses oxygen uptake by the mitochondria of the heart and interferes with energy metabolism in a manner similar to the effects of thiamin deficiency, which explained the pathophysiology of cardiomyopathy in these patients.
Discrepancies between the ETK activation test and clinical signs of thiamin deficiency have been reported previously, with several studies reporting no relationship between ETK activation results and thiamin intake (1-5).
Several deaths have resulted from cardiac failure due to thiamin deficiency when long-term TPN patients did not receive vitamins for a few weeks.
Depleted tissue stores of TPP and thiamin deficiency are interconnected, and in animal studies thiamin deficiency is correlated with large reductions in the level of mitochondrial, plasma and liver TPP, resulting in a major influence on the activities of the keto acid dehydrogenase complexes.
Polioencephalomalacia (PEM) or "blind staggers" is a disorder in ruminants that may be caused by a thiamin deficiency.