thermolabile

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thermolabile

 [ther″mo-la´bil]
easily affected by heat.

ther·mo·la·bile

(ther'mō-lā'bīl, -bil),
Subject to alteration or destruction by heat.
[thermo- + L. labilis, perishable]

thermolabile

(thûr′mō-lā′bĭl, -bīl′)
adj.
Subject to destruction, decomposition, or great change by moderate heating. Used especially of biochemical substances.

ther′mo·la·bil′i·ty (-bĭl′ĭ-tē) n.

ther·mo·la·bile

(thĕr'mō-lā'bīl)
Subject to alteration or destruction by heat.
[thermo- + L. labilis, perishable]
References in periodicals archive ?
A common genetic variant of the MTHFR gene (677 C[right arrow]T) is known to be associated with thermolability of the MTHFR enzyme with a remaining activity of around 50 per cent of the normal molecule and elevated plasma homocysteine levels, especially in those with low folic acid concentrations (3,4,17).
Unusual thermolability properties of [beta]-hexosaminidase: studies of enzyme from cultured cells and clinical implications.
The C677T (Ala-to-Val) transition, which produces thermolability and somewhat reduced enzyme activity in vitro, was first described by Kang et al.
The thermal inactivation profile showed a linear temperature-dependent thermolability (n = 10; [r.sup.2] = 0.97), with residual immunoreactivity of ~60% after 30 min at 55[degrees]C and ~10% after 30 min at 75[degrees]C.
A common mutation in the MTHFR gene (C677T) (3) produces an enzyme with partially reduced activity, which may be characterized by thermolability in vitro (4).
The thermal inactivation profile showed a linear temperature-dependent thermolability (n = 5, [r.sup.2] = 0.98), with residual immunoreactivity ~45% after 30 min at 55[degrees]C and only 6% after 75[degrees]C for 30 min.
Unusual thermolability properties of leukocyte [beta]-hexosaminidase: implications in screening for carriers of Tay-Sachs disease.
The thermal inactivation profile clearly showed a typical curve of thermolability, with residual immunoreactivity being reduced to ~34% after incubation for 30 min at 65 [degrees]C.
Moreover, in our case, after incubation for 20 min at 56 [degrees]C, the patient's lipase activity changed from 11 000 U/L to 42 U/L, in agreement with the previously described thermolability of pancreatic isoforms [7].