therapeutic range


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Related to therapeutic range: minimum effective concentration

ther·a·peu·tic range

refers to either the dosage range or blood plasma or serum concentration usually expected to achieve desired therapeutic effects. Some patients require doses (or concentrations) above or below this range. Some patients will experience drug toxicity within this range.

therapeutic range

Therapeutics The range of concentrations at which a drug or other therapeutic agent is effective with minimal toxicity to most Pts. See Clearance.

ther·a·peu·tic range

(thār'ă-pyū'tik rānj)
Either the dosage range or the blood plasma or serum concentration expected to achieve therapeutic effects.
References in periodicals archive ?
You do a disservice to patients with new-onset atrial fibrillation by using warfarin, because some patients will get into the therapeutic range but others never will.
Such discrepancies are of particular concern when the erroneous INR result is within the therapeutic range but the actual value is supratherapeutic, i.
Two consecutive INR values should be in the therapeutic range during the overlap.
He was certainly not taking enough of them to get into the therapeutic range.
If the aPTT is used as the monitor for heparin therapy, only the most accurate protocols to determine the heparin therapeutic range (HTR) should be used.
If warfarin is contraindicated, inconvenient or if therapeutic ranges have not been achieved, long-term therapy with LMWH should be considered.
Frequent monitoring to support drug dosing adjustments and also to stay within the therapeutic range has proved to be an essential element in the success of any therapy.
Hammett-Stabler (University of North Carolina-Chapel Hill) and Dasgupta (University of Texas-Houston Health Sciences Center) offer a source of information on the intended uses, pharmacokinetics, therapeutic range, toxic concentrations, bioavailability, disposition, metabolism, and excretion of commonly monitored therapeutic drugs.
Labopharm's once-daily tramadol product is based on the Company's proprietary Contramid(R) technology, which provides a dual matrix delivery system allowing both rapid and sustained drug release that maintains blood levels within the therapeutic range providing a full 24 hours of pain relief.
A prothrombin time (PT) with international normalized ratio (INR) is required after the second or third dose and then daily until consecutive INRs match within the therapeutic range, 2.
We chose case history A to focus on strict monitoring of warfarin treatment in a patient with a mechanical heart valve prosthesis and stable INR results, whereas case history B focused on INR measurement and warfarin dosage in a patient recovering from pulmonary embolism with INR above the therapeutic range.

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