therapeutic range


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Related to therapeutic range: minimum effective concentration

ther·a·peu·tic range

refers to either the dosage range or blood plasma or serum concentration usually expected to achieve desired therapeutic effects. Some patients require doses (or concentrations) above or below this range. Some patients will experience drug toxicity within this range.

therapeutic range

Therapeutics The range of concentrations at which a drug or other therapeutic agent is effective with minimal toxicity to most Pts. See Clearance.

ther·a·peu·tic range

(thār'ă-pyū'tik rānj)
Either the dosage range or the blood plasma or serum concentration expected to achieve therapeutic effects.
References in periodicals archive ?
This study supports the consensus in the medical literature that dental extractions in patients whose INR is within the therapeutic range can be done without modification of oral anticoagulant treatment.
If warfarin is contraindicated, inconvenient or if therapeutic ranges have not been achieved, long-term therapy with LMWH should be considered.
Seventy-two percent of the patients included in the analysis were outside of the therapeutic range. INR exceeding 5 was present in 11% of patients included in the analysis.
Each subject's compliance with therapy was reflected by the percentage of his/her INRs being within the therapeutic range [+ or -] 0.2.
The purpose of learning how to calculate pediatric drug doses is to ensure that the child receives the correct dose within the normal therapeutic range (17); a pediatric reference must be consulted to determine the minimum and maximum safe amounts of medication.
In treating such critically ill patients in 'Intensive care units', drug treatment should be so instituted looking forward to their organ display using a battery of selected tests as indicated in order to achieve steady state plasma concentration required within a known and safe effective therapeutic range.
31, accuses Haag Home staffers of failing to properly obtain and dispense his anti-seizure medication in the weeks before his death, allowing the level of the drugs in his system to fall below the therapeutic range. Representatives for the Haag Home did not return calls seeking comment, and the home had not filed a response to the lawsuit in court.
``His level was below the therapeutic range which would suggest he had not been taking the drug according to his doctor's orders.''
On July 19, the resident's INR level was climbing above the therapeutic range. Her physician lowered the Coumadin dosage to 2 mg daily, starting July 20, and discontinued the heparin.
The tendency during pregnancy is to give the lowest possible dose of medications, which is warranted, but as the pregnancy progresses, a woman may need more of the drug to remain in the therapeutic range. Later in pregnancy, when seizures can also be induced by other causes, such as hypertension, hyponatremia, and hypoalbuminemia, higher doses may be needed.

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