You do a disservice to patients with new-onset atrial fibrillation by using warfarin, because some patients will get into the therapeutic range
but others never will.
Such discrepancies are of particular concern when the erroneous INR result is within the therapeutic range
but the actual value is supratherapeutic, i.
Two consecutive INR values should be in the therapeutic range
during the overlap.
He was certainly not taking enough of them to get into the therapeutic range
If the aPTT is used as the monitor for heparin therapy, only the most accurate protocols to determine the heparin therapeutic range
(HTR) should be used.
The average individual time in therapeutic range
(iTTR; with a target INR of 2.
If warfarin is contraindicated, inconvenient or if therapeutic ranges
have not been achieved, long-term therapy with LMWH should be considered.
Frequent monitoring to support drug dosing adjustments and also to stay within the therapeutic range
has proved to be an essential element in the success of any therapy.
Hammett-Stabler (University of North Carolina-Chapel Hill) and Dasgupta (University of Texas-Houston Health Sciences Center) offer a source of information on the intended uses, pharmacokinetics, therapeutic range
, toxic concentrations, bioavailability, disposition, metabolism, and excretion of commonly monitored therapeutic drugs.
Labopharm's once-daily tramadol product is based on the Company's proprietary Contramid(R) technology, which provides a dual matrix delivery system allowing both rapid and sustained drug release that maintains blood levels within the therapeutic range
providing a full 24 hours of pain relief.
A prothrombin time (PT) with international normalized ratio (INR) is required after the second or third dose and then daily until consecutive INRs match within the therapeutic range
We chose case history A to focus on strict monitoring of warfarin treatment in a patient with a mechanical heart valve prosthesis and stable INR results, whereas case history B focused on INR measurement and warfarin dosage in a patient recovering from pulmonary embolism with INR above the therapeutic range