therapeutic misadventure

therapeutic misadventure

Boo-boo An unintentional–or 'functional' overdose of a therapeutic agent due to unanticipated effects of extraneous factors–eg, acetaminophen hepatotoxicity in alcoholics, due to cytochrome P-450 induction. See Opportunity for improvement.

therapeutic misadventure

A drug experience that results in an undesired or unintended response to drug therapy. The term includes adverse drug reactions and medication errors. Synonym: medication misadventure See: adverse drug reaction; medication error
References in periodicals archive ?
This is a set up for misinformation and therapeutic misadventure. Education has as strong an evidence base as any available AD intervention.
Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure. Hepatology 1995; 22:767-773.
This type of investigation augurs that objective biomarkers might halt the unrelenting misdiagnosis of bipolar depression as MDD and end the iatrogenic suffering of millions of bipolar disorder patients who became victims of a "therapeutic misadventure."
Kasturi is right about the importance of arriving at an accurate diagnosis before embarking on treatment; otherwise, patients will suffer from "therapeutic misadventures." I have observed this being experienced by some of the patients referred to me because of "treatment resistance."
Our case demonstrates that failure of medical practitioners to effectively communicate and the lack of knowledge of odontogenic cutaneous fistulas lead to diagnostic and therapeutic misadventures as seen in this patient.
On the other hand, the therapeutic misadventures, illicit drug ingestion or attempted suicide by using of harmful substances is a major worldwide public health problem that causes both a significant cost and severe heath problems, even death.
Patient dissatisfaction following such diagnostic and therapeutic misadventures is understandably high.
Looking just at calls for what we would call therapeutic misadventures, the drop was even greater, of 54 percent from, 41 to 19.
Therapeutic misadventures with acetaminophen: hepatotoxicity after multiple doses in children.
"There is a recognition by the profession of pharmacy that all of the basic tenets of pharmaceutical care designed to optimize health outcomes and minimize therapeutic misadventures apply to nonprescription drug therapy as well as prescription drug therapy," he said.
Second, as a scientist who saw many well-intentioned therapeutic misadventures result in far more harm than good, he argues for randomized clinical trials to define the benefits and risks of innovative treatments.
But Ahmann offered the most pointed criticisms: When blood clots "could occur [in] up to 1.5 percent" of the study's participants, and uterine cancer in almost as many, "one really wonders whether or not the therapeutic benefits might be outweighed by therapeutic misadventures."
Full browser ?